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1

Genetic Variants and Tumor Immune Microenvironment: Clues for Targeted Therapies in Inflammatory Breast Cancer (IBC)

المؤلفون: Rajeswari Nagarathinam, Michael Slifker, Katherine Alpaugh, Jianming Pei, Kathy Q. Cai, Yulan Gong, Massimo Cristofanilli, Elias Obeid, Zachary Hasse, Christopher Sebastiano, Jennifer S. Winn, Sandra V. Fernandez, Eric A. Ross, Lorenzo Gerratana, Julio E. Noriega, Maria F. Arisi

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8924, p 8924 (2021)
Volume 22
Issue 16

مصطلحات موضوعية: programmed cell death-ligand 1 (PD-L1), tumor infiltrating lymphocytes (TILs), Receptor, ErbB-2, medicine.medical_treatment, B7-H1 Antigen, Tumor Microenvironment, poly (ADP-ribose) polymerase, Molecular Targeted Therapy, Biology (General), skin and connective tissue diseases, immune checkpoint inhibitors (ICIs), Spectroscopy, CD20, biology, FOXP3, High-Throughput Nucleotide Sequencing, General Medicine, Middle Aged, Prognosis, Computer Science Applications, Gene Expression Regulation, Neoplastic, Survival Rate, Chemistry, Receptors, Estrogen, PARP inhibitor, Immunohistochemistry, RAD51C, Female, Inflammatory Breast Neoplasms, Receptors, Progesterone, Cell-Free Nucleic Acids, Adult, QH301-705.5, PALB2, Inflammatory breast cancer, Catalysis, Article, Inorganic Chemistry, Lymphocytes, Tumor-Infiltrating, medicine, Biomarkers, Tumor, cell-free DNA (cfDNA), Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Aged, Retrospective Studies, business.industry, Organic Chemistry, Immunotherapy, medicine.disease, Mutation, biology.protein, Cancer research, business, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b574cfb17b2590c27702c1cc7e4f4b8Test
https://pubmed.ncbi.nlm.nih.gov/34445631Test

2

Analysis of

المؤلفون: Vladimir, Sobolev, Anastasia, Nesterova, Anna, Soboleva, Alexandre, Mezentsev, Evgenia, Dvoriankova, Anastas, Piruzyan, Elena, Denisova, Olga, Melnichenko, Irina, Korsunskaya

المصدر: International Journal of Molecular Sciences

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::919f551688a397af25c606a230137342Test
https://pubmed.ncbi.nlm.nih.gov/34445309Test

3

hTERT-Driven Immortalization of RDEB Fibroblast and Keratinocyte Cell Lines Followed by Cre-Mediated Transgene Elimination

المؤلفون: Rustam H. Ziganshin, Arkadii K. Beilin, Alexandra L. Rippa, Ekaterina A. Vorotelyak, A. V. Vasiliev, Maxim M. Perfilov, Nadezhda A. Evtushenko, Nadya G. Gurskaya, Elena V. Alpeeva, Anastasiya V. Kosykh, E. B. Dashinimaev

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3809, p 3809 (2021)

مصطلحات موضوعية: Keratinocytes, Male, Proteomics, Fluorescent Antibody Technique, Cre recombination, immortalization, fibroblast, Extracellular matrix, lcsh:Chemistry, Gene Order, COL7A1, Transgenes, Child, Homologous Recombination, Telomerase, lcsh:QH301-705.5, Cellular Senescence, Spectroscopy, Cell Line, Transformed, Polycomb Repressive Complex 1, RDEB, Chemistry, General Medicine, Middle Aged, Immunohistochemistry, Epidermolysis Bullosa Dystrophica, Computer Science Applications, Cell biology, medicine.anatomical_structure, Gene Knockdown Techniques, Female, Keratinocyte, hTERT, bmi-1, Adult, secretomes, Adolescent, Genetic Vectors, Primary Cell Culture, keratinocyte, Article, Catalysis, Inorganic Chemistry, Young Adult, stratification, Dermis, medicine, Humans, Physical and Theoretical Chemistry, Progenitor cell, Fibroblast, Molecular Biology, Cell Proliferation, Integrases, Organic Chemistry, Fibroblasts, lcsh:Biology (General), lcsh:QD1-999, Cell culture, Mutation, Ectopic expression, 3D skin equivalent, Immortalised cell line, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a71ac837e97a830f60a22e9d9c78f7eTest

4

PD-L1 Status in Gastric Cancers, Association with the Transcriptional, Growth Factors, AKT/mTOR Components Change, and Autophagy Initiation

المؤلفون: Alexey Dobrodeev, Sergei Afanas’ev, L. V. Spirina, Dmitry Kostromitsky, Olga V Cheremisina, Alexandra Avgustinovich, Maxim Volkov

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 11176, p 11176 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20

مصطلحات موضوعية: Male, Programmed Cell Death 1 Receptor, Pembrolizumab, medicine.disease_cause, B7-H1 Antigen, Tumor Status, LC3B, Biology (General), Spectroscopy, biology, TOR Serine-Threonine Kinases, General Medicine, Middle Aged, Immunohistochemistry, Computer Science Applications, Gene Expression Regulation, Neoplastic, Chemistry, Intercellular Signaling Peptides and Proteins, Female, Microtubule-Associated Proteins, Signal Transduction, Adult, PD-L1, QH301-705.5, Article, Catalysis, Inorganic Chemistry, Young Adult, Stomach Neoplasms, growth factors, Autophagy, Biomarkers, Tumor, medicine, Humans, transcriptional factors, Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, gastric cancers, business.industry, Organic Chemistry, Cancer, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, Cancer research, biology.protein, AKT/mTOR component, business, Carcinogenesis, Proto-Oncogene Proteins c-akt, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a688b59aeb6683480132d95296105a1dTest
https://doi.org/10.3390/ijms222011176Test

5

Prognostic Value of the Overexpression of Fatty Acid Metabolism-Related Enzymes in Squamous Cell Carcinoma of the Head and Neck

المؤلفون: Yu Shao Kuo, Sheng Hsiang Lin, Hung Pin Lin, Pao Shu Wu, Wen Yu Huang, Ying Wen Su

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 6851, p 6851 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 18

مصطلحات موضوعية: Oncology, Male, squamous cell carcinoma, head and neck, lcsh:Chemistry, chemistry.chemical_compound, lcsh:QH301-705.5, Spectroscopy, long-chain acyl-CoA dehydrogenase, Aged, 80 and over, Tissue microarray, biology, Hazard ratio, Acyl-CoA Dehydrogenase, Long-Chain, Fatty Acids, General Medicine, Middle Aged, Prognosis, Immunohistochemistry, Computer Science Applications, Up-Regulation, Fatty acid synthase, fatty acid metabolism, Head and Neck Neoplasms, Female, Adult, medicine.medical_specialty, Catalysis, Long-chain acyl-CoA dehydrogenase, Article, Inorganic Chemistry, Carnitine palmitoyltransferase 1, Internal medicine, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, Aged, Neoplasm Staging, Proportional Hazards Models, Fatty acid metabolism, Carnitine O-Palmitoyltransferase, business.industry, Squamous Cell Carcinoma of Head and Neck, Organic Chemistry, Lipid metabolism, stomatognathic diseases, chemistry, lcsh:Biology (General), lcsh:QD1-999, Tissue Array Analysis, biology.protein, Fatty Acid Synthases, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccf74a2d66bb62c23494af366c03c0fTest
https://www.mdpi.com/1422-0067/21/18/6851Test

6

Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto’s Thyroiditis

المؤلفون: Axel De Greef, Chantal Daumerie, Marc de Bournonville, Michael Hepp, Marie-Christine Many, Benoît Lengelé, Marian Ludgate, Michel Mourad, Julie Craps, Virginie Joris, Alexis Werion, Catherine Behets, Christine de Ville de Goyet

المساهمون: UCL - SSS/IREC/MORF - Pôle de Morphologie, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/FATH - Pôle de Pharmacologie et thérapeutique, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de chirurgie plastique, UCL - (SLuc) Service de soins intensifs, UCL - (SLuc) Service d'endocrinologie et de nutrition, UCL - (SLuc) Service de chirurgie et transplantation abdominale

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 3806, p 3806 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 8
International journal of molecular sciences, Vol. 22, no. 8, p. 3806 [1-17] (2021)

مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, 0301 basic medicine, endocrine system diseases, Thyroid Gland, Fluorescent Antibody Technique, Autoimmunity, Thyroid Function Tests, medicine.disease_cause, lcsh:Chemistry, Superoxide Dismutase-1, 0302 clinical medicine, Sirtuin 1, T-Lymphocyte Subsets, oxidative stress, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, Thymocytes, biology, Chemistry, Hashimoto’s thyroiditis, General Medicine, Middle Aged, Immunohistochemistry, Computer Science Applications, Vascular endothelial growth factor A, Catalase, 030220 oncology & carcinogenesis, NADPH Oxidase 2, Cytokines, Female, Adult, medicine.medical_specialty, HIF-1α, Hashimoto Disease, Peroxiredoxin 1, Models, Biological, Article, Catalysis, Autoimmune Diseases, NOX4, Inorganic Chemistry, Superoxide dismutase, Young Adult, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, medicine, Humans, Sirtuin1, Physical and Theoretical Chemistry, Molecular Biology, Reactive oxygen species, Organic Chemistry, Th1 Cells, Hypoxia-Inducible Factor 1, alpha Subunit, 030104 developmental biology, Endocrinology, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, biology.protein, Reactive Oxygen Species, Biomarkers, Oxidative stress

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb20093ed35c670448f9a120dfcdf586Test
https://doi.org/10.3390/ijms22083806Test

7

Immunohistochemical Evaluation of Aquaporin-4 and its Correlation with CD68, IBA-1, HIF-1α, GFAP, and CD15 Expressions in Fatal Traumatic Brain Injury

المؤلفون: Aniello Maiese, Paola Frati, Matteo Scopetti, Emanuela Turillazzi, Santina Cantatore, Margherita Neri, Luigi Cipolloni, Vittorio Fineschi, Alessandro Santurro, Francesco Sessa, Raffaele La Russa, Marco Di Paolo, Rosanna Zamparese, Alessandro Frati

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3544 (2018)
Volume 19
Issue 11

مصطلحات موضوعية: 0301 basic medicine, Traumatic, Male, Pathology, Excitotoxicity, Brain Edema, genetic analysis, medicine.disease_cause, computer vision and pattern recognition, lcsh:Chemistry, 0302 clinical medicine, Brain Injuries, Traumatic, lcsh:QH301-705.5, Tomography, Spectroscopy, Glial fibrillary acidic protein, biology, traumatic brain injury, Microfilament Proteins, General Medicine, Organ Size, Middle Aged, Immunohistochemistry, Computer Science Applications, CD, X-Ray Computed, DNA-Binding Proteins, Aquaporin 4, Cerebral blood flow, aquaporin, computed tomography (CT) scan, edema, hypoxia, microglia activation, adult, aged, antigens, Differentiation, myelomonocytic, aquaporin 4, base sequence, brain edema, brain injuries, traumatic, DNA-binding proteins, female, glial fibrillary acidic protein, humans, hypoxia-inducible factor 1, alpha subunit, immunohistochemistry, lewis x antigen, male, middle aged, organ size, tomography, x-ray computed, young adult, catalysis, molecular biology, spectroscopy, computer science applications, 1707, physical and theoretical chemistry, organic chemistry, inorganic chemistry, Female, Hypoxia-Inducible Factor 1, medicine.symptom, Aquaporin, Computed tomography (CT) scan, Edema, Genetic analysis, Hypoxia, Microglia activation, Traumatic brain injury, Adult, Aged, Antigens, CD, Antigens, Differentiation, Myelomonocytic, Base Sequence, Calcium-Binding Proteins, Glial Fibrillary Acidic Protein, Humans, Hypoxia-Inducible Factor 1, alpha Subunit, Lewis X Antigen, Tomography, X-Ray Computed, Young Adult, medicine.medical_specialty, Socio-culturale, alpha Subunit, Neuroprotection, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, medicine, Physical and Theoretical Chemistry, Antigens, Molecular Biology, Neuroinflammation, business.industry, Organic Chemistry, Myelomonocytic, Hypoxia (medical), medicine.disease, nervous system diseases, 030104 developmental biology, nervous system, lcsh:Biology (General), lcsh:QD1-999, Brain Injuries, biology.protein, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63d517619a3f16eacace813a346c4e9Test
https://pubmed.ncbi.nlm.nih.gov/30423808Test

8

Aquaporin 1, 3, and 5 Patterns in Salivary Gland Mucoepidermoid Carcinoma: Expression in Surgical Specimens and an In Vitro Pilot Study

المؤلفون: Fernanda de Paula, Clovis Antonio Lopes Pinto, Katia Klug Oliveira, Milena Monteiro de Souza, Silvia Vanessa Lourenço, Ágatha Nagli de Mello Gomes, Márcia Martins Marques, Mérin Barbara Stamboni, Luiz Paulo Kowalski, Barbara Beltrame Bettim, Cláudia Malheiros Coutinho-Camillo, Victor E. Arana-Chavez, Claudia Fabiana Joca de Arruda

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1287 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 4

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Saliva, Pilot Projects, medicine.disease_cause, lcsh:Chemistry, 0302 clinical medicine, aquaporins, lcsh:QH301-705.5, Spectroscopy, Salivary gland, General Medicine, Middle Aged, Salivary Gland Neoplasms, Phenotype, Computer Science Applications, mucoepidermoid carcinoma, Survival Rate, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Aquaporin 1, immunohistochemistry, Immunohistochemistry, Female, Salivary Gland Mucoepidermoid Carcinoma, Adult, medicine.medical_specialty, Biology, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Mucoepidermoid carcinoma, Cell Line, Tumor, medicine, Humans, Physical and Theoretical Chemistry, immunofluorescence, Molecular Biology, Aquaporin 3, electron microscopy, Organic Chemistry, Epithelial Cells, medicine.disease, Aquaporin 5, Microscopy, Electron, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Carcinoma, Mucoepidermoid, Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94d4903ffa5e17cc6ca020c30b87c21Test
https://www.mdpi.com/1422-0067/21/4/1287Test

9

Prognostic relevance of RIP140 and ERβ expression in unifocal versus multifocal breast cancers: a preliminary report

المؤلفون: Sven Mahner, Sophie Sixou, Doris Mayr, Nina Ditsch, Christina Kühn, Katharina Müller, Vincent Cavaillès, Tobias Weissenbacher, Udo Jeschke, Stéphan Jalaguier, Nadia Harbeck

المساهمون: Department of Obstetrics and Gynecology [Munich, Germany], University-Hospital Munich-Großhadern [München]-Ludwig Maximilian University [Munich] (LMU), Faculté des Sciences Pharmaceutiques, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Institut de recherche en cancérologie de Montpellier (IRCM - U896 Inserm - UM1), CRLCC Val d'Aurelle - Paul Lamarque-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 1 (UM1), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Department of Pathology [Munich, Germany], Ludwig Maximilian University [Munich] (LMU), S.S. salary was supported by the University Paul Sabatier in Toulouse (France). The project wassupported by the 'Centre de Coopération Universitaire Franco-Bavarois' (CCUFB) or 'Bayerisch-FranzösischesHochschulzentrum' (BFHZ), Project funding FK19-15., Cavailles, Vincent, Université Montpellier 1 (UM1)-CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2019, 20 (2), pp.418. ⟨10.3390/ijms20020418⟩
International Journal of Molecular Sciences, Vol 20, Iss 2, p 418 (2019)
Volume 20
Issue 2
International Journal of Molecular Sciences, 2019, 20 (2), pp.418. ⟨10.3390/ijms20020418⟩

مصطلحات موضوعية: tumor focality, Estrogen receptor, Gene Expression, Kaplan-Meier Estimate, lcsh:Chemistry, 0302 clinical medicine, Preliminary report, Medicine, lcsh:QH301-705.5, Spectroscopy, 0303 health sciences, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, estrogen receptors, General Medicine, Middle Aged, Prognosis, Immunohistochemistry, Computer Science Applications, Nuclear Receptor Interacting Protein 1, Tumor Burden, 030220 oncology & carcinogenesis, Female, Adult, [SDV.CAN]Life Sciences [q-bio]/Cancer, Breast Neoplasms, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Breast cancer, breast cancer, [SDV.CAN] Life Sciences [q-bio]/Cancer, Biomarkers, Tumor, Estrogen Receptor beta, Humans, In patient, ddc:610, Physical and Theoretical Chemistry, Molecular Biology, 030304 developmental biology, Aged, Neoplasm Staging, business.industry, Organic Chemistry, medicine.disease, lcsh:Biology (General), lcsh:QD1-999, Nuclear receptor, RIP140, LCoR, Cancer research, LCOR, Neoplasm Grading, business, Corepressor, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c2bf6496d12a7e41909900b46b007cTest
https://pubmed.ncbi.nlm.nih.gov/30669416Test

10

Casein Kinase 1 Epsilon Expression Predicts Poorer Prognosis in Low T-Stage Oral Cancer Patients

المؤلفون: Yueh-Min Lin, Mei-Wen Chen, Shu-Hui Lin, Chih-Jung Chen, Kun-Tu Yeh, Chung-Min Yeh, Hsiao-Fang Hung, Shun-Fa Yang

المصدر: International Journal of Molecular Sciences; Volume 15; Issue 2; Pages: 2876-2891
International Journal of Molecular Sciences, Vol 15, Iss 2, Pp 2876-2891 (2014)
International Journal of Molecular Sciences

مصطلحات موضوعية: Adult, Male, Casein Kinase 1 epsilon, overall survival, casein kinase 1 epsilon (CK1ɛ), Kaplan-Meier Estimate, Article, Catalysis, lcsh:Chemistry, Inorganic Chemistry, Humans, Medicine, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Survival rate, Spectroscopy, Aged, Neoplasm Staging, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, Mouth neoplasm, Proportional hazards model, Kinase, business.industry, Organic Chemistry, Hazard ratio, Cancer, General Medicine, Middle Aged, oral cancer, Casein Kinase Iepsilon, Prognosis, medicine.disease, Immunohistochemistry, casein kinase 1 epsilon (CK1ε), Computer Science Applications, lcsh:Biology (General), lcsh:QD1-999, Immunology, Carcinoma, Squamous Cell, Cancer research, Female, Mouth Neoplasms, Casein kinase 1, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32421810c0cb5830f357c14634c84e7Test
https://doi.org/10.3390/ijms15022876Test

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