نتائج البحث

1

Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin

المؤلفون: Noo Ri Lee, Beom Jun Kim, Kyong Oh Shin, Eun Jung Kim, Gareth G. Lavery, Hyun Jee Hwang, Kyungho Park, Young Bin Lee, Solam Lee, Chung Hyeok Lee, Eung Ho Choi, Sung Jay Choe

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5750, p 5750 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, 11-beta-hydroxysteroid dehydrogenase type 1, 030207 dermatology & venereal diseases, chemistry.chemical_compound, Mice, 0302 clinical medicine, Corticosterone, 11β-hydroxysteroid dehydrogenase type 1, Biology (General), Spectroscopy, Barrier function, Mice, Knockout, biology, integumentary system, glucocorticoids, General Medicine, Middle Aged, Computer Science Applications, Chemistry, Knockout mouse, Cytokines, Female, Inflammation Mediators, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Adult, medicine.medical_specialty, endocrine system, QH301-705.5, Catalysis, Permeability, Article, Inorganic Chemistry, 03 medical and health sciences, Young Adult, Lipid biosynthesis, Internal medicine, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Aged, Transepidermal water loss, Organic Chemistry, Hairless, Skin Aging, 030104 developmental biology, Endocrinology, chemistry, Gene Expression Regulation, biology.protein, Cortisone, Epidermis, barrier function, Biomarkers, epidermal lipids

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8084c8f5c816d4e38a571e81ad199fTest
https://pubmed.ncbi.nlm.nih.gov/34072239Test

2

Clinical and Prognostic Value of Antigen-Presenting Cells with PD-L1/PD-L2 Expression in Ovarian Cancer Patients

المؤلفون: Anna Pawłowska, Bartłomiej Barczyński, Iwona Wertel, Agnieszka Kwiatkowska, Rafał Tarkowski, Dorota Suszczyk, Jan Kotarski, Agata Chudzik

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11563, p 11563 (2021)

مصطلحات موضوعية: Myeloid, medicine.medical_treatment, Carcinoma, Ovarian Epithelial, B7-H1 Antigen, Medicine, Ascitic Fluid, Biology (General), Spectroscopy, Aged, 80 and over, Ovarian Neoplasms, medicine.diagnostic_test, biology, General Medicine, Middle Aged, Prognosis, Computer Science Applications, Chemistry, medicine.anatomical_structure, ovarian cancer, Female, immunotherapy, Adult, QH301-705.5, Antigen-Presenting Cells, Catalysis, Article, Flow cytometry, Inorganic Chemistry, Young Adult, PD-L1, Humans, tumor microenvironment, Physical and Theoretical Chemistry, Antigen-presenting cell, Molecular Biology, QD1-999, Aged, Tumor microenvironment, business.industry, Peritoneal fluid, Organic Chemistry, Immunotherapy, Dendritic Cells, programmed cell death pathway, medicine.disease, Programmed Cell Death 1 Ligand 2 Protein, biology.protein, Cancer research, immune suppression, business, Ovarian cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a8fc4cef4054f54c194e1ff23cad38Test
http://europepmc.org/articles/PMC8583913Test

3

PD-1 and PD-L1 Expression on Circulating Lymphocytes as a Marker of Epstein-Barr Virus Reactivation-Associated Proliferative Glomerulonephritis

المؤلفون: Anna Hymos, Wojciech Załuska, Iwona Smarz-Widelska, Ewelina Grywalska, Krzysztof Gosik, Paulina Niedźwiedzka-Rystwej, Izabela Korona-Glowniak, Jacek Roliński, Jarosław Ludian, Sebastian Mertowski

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8001, p 8001 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Epstein-Barr Virus Infections, T-Lymphocytes, Programmed Cell Death 1 Receptor, medicine.disease_cause, B7-H1 Antigen, lcsh:Chemistry, Epstein–Barr virus, immunology, 0302 clinical medicine, PD-1, CD8+ T lymphocyte, lcsh:QH301-705.5, Spectroscopy, B-Lymphocytes, medicine.diagnostic_test, biology, CD19+ B lymphocyte, Glomerulonephritis, General Medicine, Middle Aged, programmed cell death protein 1, Computer Science Applications, Up-Regulation, 030220 oncology & carcinogenesis, Female, Adult, PD-L1, Programmed cell death, programmed death-ligand 1, Peripheral blood mononuclear cell, Catalysis, Virus, Article, Flow cytometry, Inorganic Chemistry, 03 medical and health sciences, Young Adult, Antigen, EBV, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, Aged, CD4+ T lymphocyte, business.industry, Organic Chemistry, medicine.disease, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, ROC Curve, Case-Control Studies, Immunology, biology.protein, Leukocytes, Mononuclear, business, glomerulonephritis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372c9bec7d09fa587bba4d66a2497702Test

4

Sirtuin 1 and Sirtuin 3 in Granulosa Cell Tumors

المؤلفون: Rina Meidan, Nina Schmid, Artur Mayerhofer, Kim-Gwendolyn Dietrich, Doris Mayr, Ignasi Forné, Magdalena Szymanska, Alexander Burges

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 2047, p 2047 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4

مصطلحات موضوعية: 0301 basic medicine, Cell, lcsh:Chemistry, 0302 clinical medicine, Sirtuin 1, Sirtuin 3, RNA, Small Interfering, lcsh:QH301-705.5, Spectroscopy, Granulosa Cell Tumor, Aged, 80 and over, siRNA silencing, General Medicine, Middle Aged, Computer Science Applications, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Sirtuin, Adult, Programmed cell death, SIRT3, Adolescent, Carbazoles, Down-Regulation, Biology, Heterocyclic Compounds, 2-Ring, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Young Adult, Cell Line, Tumor, medicine, Humans, Proliferation Marker, Gene Silencing, RNA, Messenger, Physical and Theoretical Chemistry, Molecular Biology, Aged, Cell growth, Organic Chemistry, EX 527, KGN, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Apoptosis, Cancer research, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd05533800a40d355743143c69dc3a2Test
https://pubmed.ncbi.nlm.nih.gov/33669567Test

5

PD-L1 Status in Gastric Cancers, Association with the Transcriptional, Growth Factors, AKT/mTOR Components Change, and Autophagy Initiation

المؤلفون: Alexey Dobrodeev, Sergei Afanas’ev, L. V. Spirina, Dmitry Kostromitsky, Olga V Cheremisina, Alexandra Avgustinovich, Maxim Volkov

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 11176, p 11176 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20

مصطلحات موضوعية: Male, Programmed Cell Death 1 Receptor, Pembrolizumab, medicine.disease_cause, B7-H1 Antigen, Tumor Status, LC3B, Biology (General), Spectroscopy, biology, TOR Serine-Threonine Kinases, General Medicine, Middle Aged, Immunohistochemistry, Computer Science Applications, Gene Expression Regulation, Neoplastic, Chemistry, Intercellular Signaling Peptides and Proteins, Female, Microtubule-Associated Proteins, Signal Transduction, Adult, PD-L1, QH301-705.5, Article, Catalysis, Inorganic Chemistry, Young Adult, Stomach Neoplasms, growth factors, Autophagy, Biomarkers, Tumor, medicine, Humans, transcriptional factors, Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, gastric cancers, business.industry, Organic Chemistry, Cancer, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, Cancer research, biology.protein, AKT/mTOR component, business, Carcinogenesis, Proto-Oncogene Proteins c-akt, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a688b59aeb6683480132d95296105a1dTest
https://doi.org/10.3390/ijms222011176Test

6

Oxidative Stress and Analysis of Selected SNPs of ACHE (rs 2571598), BCHE (rs 3495), CAT (rs 7943316), SIRT1 (rs 10823108), GSTP1 (rs 1695), and Gene GSTM1, GSTT1 in Chronic Organophosphates Exposed Groups from Cameroon and Pakistan

المؤلفون: Syed M. Nurulain, Rabia Habib, Leonel Javeres Mbah Ntepe, Sajida Batool, Ngondi Judith Laure, Eugenie Nepovimova, Saqlain Raza, Kamil Kuca

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 17

مصطلحات موضوعية: Male, 010501 environmental sciences, Pharmacology, medicine.disease_cause, 01 natural sciences, chemistry.chemical_compound, GSTP1, 0302 clinical medicine, Sirtuin 1, Malondialdehyde, Pakistan, Cameroon, cholinergic enzymes, Spectroscopy, Glutathione Transferase, biology, General Medicine, Middle Aged, toxicogenetics, Catalase, Acetylcholinesterase, Glutathione, Computer Science Applications, antioxidants, Female, SNPs, Adult, Adolescent, GPI-Linked Proteins, Polymorphism, Single Nucleotide, Catalysis, Article, Inorganic Chemistry, Superoxide dismutase, 03 medical and health sciences, Young Adult, Organophosphorus Compounds, organophosphates, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, 0105 earth and related environmental sciences, Cholinesterase, Organic Chemistry, Environmental Exposure, Oxidative Stress, chemistry, Glutathione S-Transferase pi, Butyrylcholinesterase, biology.protein, Gene-Environment Interaction, 030217 neurology & neurosurgery, Oxidative stress

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b949386dcb0d84220f2a9147a25999Test
http://europepmc.org/articles/PMC7503738Test

7

Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto’s Thyroiditis

المؤلفون: Axel De Greef, Chantal Daumerie, Marc de Bournonville, Michael Hepp, Marie-Christine Many, Benoît Lengelé, Marian Ludgate, Michel Mourad, Julie Craps, Virginie Joris, Alexis Werion, Catherine Behets, Christine de Ville de Goyet

المساهمون: UCL - SSS/IREC/MORF - Pôle de Morphologie, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/FATH - Pôle de Pharmacologie et thérapeutique, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de chirurgie plastique, UCL - (SLuc) Service de soins intensifs, UCL - (SLuc) Service d'endocrinologie et de nutrition, UCL - (SLuc) Service de chirurgie et transplantation abdominale

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 3806, p 3806 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 8
International journal of molecular sciences, Vol. 22, no. 8, p. 3806 [1-17] (2021)

مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, 0301 basic medicine, endocrine system diseases, Thyroid Gland, Fluorescent Antibody Technique, Autoimmunity, Thyroid Function Tests, medicine.disease_cause, lcsh:Chemistry, Superoxide Dismutase-1, 0302 clinical medicine, Sirtuin 1, T-Lymphocyte Subsets, oxidative stress, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, Thymocytes, biology, Chemistry, Hashimoto’s thyroiditis, General Medicine, Middle Aged, Immunohistochemistry, Computer Science Applications, Vascular endothelial growth factor A, Catalase, 030220 oncology & carcinogenesis, NADPH Oxidase 2, Cytokines, Female, Adult, medicine.medical_specialty, HIF-1α, Hashimoto Disease, Peroxiredoxin 1, Models, Biological, Article, Catalysis, Autoimmune Diseases, NOX4, Inorganic Chemistry, Superoxide dismutase, Young Adult, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, medicine, Humans, Sirtuin1, Physical and Theoretical Chemistry, Molecular Biology, Reactive oxygen species, Organic Chemistry, Th1 Cells, Hypoxia-Inducible Factor 1, alpha Subunit, 030104 developmental biology, Endocrinology, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, biology.protein, Reactive Oxygen Species, Biomarkers, Oxidative stress