نتائج البحث

1

Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin

المؤلفون: Noo Ri Lee, Beom Jun Kim, Kyong Oh Shin, Eun Jung Kim, Gareth G. Lavery, Hyun Jee Hwang, Kyungho Park, Young Bin Lee, Solam Lee, Chung Hyeok Lee, Eung Ho Choi, Sung Jay Choe

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5750, p 5750 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, 11-beta-hydroxysteroid dehydrogenase type 1, 030207 dermatology & venereal diseases, chemistry.chemical_compound, Mice, 0302 clinical medicine, Corticosterone, 11β-hydroxysteroid dehydrogenase type 1, Biology (General), Spectroscopy, Barrier function, Mice, Knockout, biology, integumentary system, glucocorticoids, General Medicine, Middle Aged, Computer Science Applications, Chemistry, Knockout mouse, Cytokines, Female, Inflammation Mediators, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Adult, medicine.medical_specialty, endocrine system, QH301-705.5, Catalysis, Permeability, Article, Inorganic Chemistry, 03 medical and health sciences, Young Adult, Lipid biosynthesis, Internal medicine, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Aged, Transepidermal water loss, Organic Chemistry, Hairless, Skin Aging, 030104 developmental biology, Endocrinology, chemistry, Gene Expression Regulation, biology.protein, Cortisone, Epidermis, barrier function, Biomarkers, epidermal lipids

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8084c8f5c816d4e38a571e81ad199fTest
https://pubmed.ncbi.nlm.nih.gov/34072239Test

2

Analysis of Results of Specific IgE in 100 Atopic Dermatitis Patients with the Use of Multiplex Examination ALEX2—Allergy Explorer

المؤلفون: Jarmila Čelakovská, R. Vaňková, Josef Bukac, Jan Krejsek, Ctirad Andrýs, Eva Cermakova, Hana Skalská

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5286, p 5286 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Allergy, Lipocalin, ALEX2 Allergy Explorer, medicine.disease_cause, Immunoglobulin E, 0302 clinical medicine, Allergen, Fel d 1, Biology (General), Spectroscopy, Sensitization, Czech Republic, severity of atopic dermatitis, biology, atopic dermatitis, Pyroglyphidae, General Medicine, Atopic dermatitis, Allergen extract, Middle Aged, molecular components, Computer Science Applications, Chemistry, medicine.anatomical_structure, Pollen, Female, Adult, Adolescent, QH301-705.5, Catalysis, Article, Dermatitis, Atopic, Inorganic Chemistry, 03 medical and health sciences, disturbed epidermal barrier, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Aged, Skin Tests, allergic rhinitis, Organic Chemistry, asthma bronchiale, Allergens, medicine.disease, Rhinitis, Allergic, Asthma, 030104 developmental biology, 030228 respiratory system, Immunology, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476ac6d939dad0a117cd309189810e00Test

3

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

المؤلفون: Birgit Knebel, Jorg Kotzka, Hadi Al-Hasani, Yves Van Nieuwenhove, Tina Hörbelt, David Monteiro Barbosa, Aleksandra Nikolic, Dirk Müller-Wieland, Frederique Van de Velde, Sylvia Jacob, Pia Fahlbusch, Bruno Lapauw, D. Margriet Ouwens

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences, Vol 21, Iss 4144, p 4144 (2020)
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International journal of molecular sciences 21(11), 4144 (2020). doi:10.3390/ijms21114144 special issue: "Special Issue "Mechanisms of Insulin Resistance at the Crossroad of Obesity with Associated Metabolic Abnormalities and Cognitive Dysfunction" / Special Issue Editors: Prof. Dr. Melania Manco, Guest Editor; Prof. Dr. Amalia Gastaldelli, Guest Editor"

مصطلحات موضوعية: 0301 basic medicine, Male, SREBP-1c, PATHOGENESIS, LIPOTOXICITY, DISEASE, lcsh:Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Medicine and Health Sciences, Insulin-Like Growth Factor I, Beta oxidation, lcsh:QH301-705.5, Spectroscopy, INSULIN-RESISTANCE, Chemistry, CHOLESTEROL, Fatty liver, General Medicine, Middle Aged, fatty liver progression, Computer Science Applications, ADIPOSE-TISSUE, Lipotoxicity, OBESITY, Lipogenesis, Sterol Regulatory Element Binding Protein 1, Adult, medicine.medical_specialty, de novo, fatty liver metabolism, 030209 endocrinology & metabolism, Mice, Transgenic, SCORING, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Insulin resistance, LIPID-METABOLISM, Internal medicine, NAFLD, medicine, Animals, Humans, Obesity, Physical and Theoretical Chemistry, Molecular Biology, lipogenesis, Cholesterol, Organic Chemistry, Body Weight, Lipid metabolism, medicine.disease, IGF system, Mice, Inbred C57BL, Insulin-Like Growth Factor Binding Protein 2, 030104 developmental biology, Endocrinology, Insulin-Like Growth Factor Binding Protein 3, de novo lipogenesis, lcsh:Biology (General), lcsh:QD1-999, Case-Control Studies, Hepatocytes, IGFBP2, methylation, Steatohepatitis, Insulin Resistance, REDUCED EXPRESSION, Energy Metabolism, SYSTEM

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f008bb6fa680916ff2295140c4a23bTest

4

Thrombin Upregulates PAI-1 and Mesothelial–Mesenchymal Transition Through PAR-1 and Contributes to Tuberculous Pleural Fibrosis

المؤلفون: Cheng Ying Hsieh, Joen Rong Sheu, Wei Lin Chen, Chih Hao Yang, Jie Heng Tsai, Chi Li Chung

المصدر: International Journal of Molecular Sciences, Vol 20, Iss 20, p 5076 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 20

مصطلحات موضوعية: 0301 basic medicine, Male, Mesoderm, lcsh:Chemistry, chemistry.chemical_compound, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, lcsh:QH301-705.5, Spectroscopy, Aged, 80 and over, mesothelial–mesenchymal transition, biology, General Medicine, Exudates and Transudates, Middle Aged, respiratory system, thrombin, Computer Science Applications, Effusion, Plasminogen activator inhibitor-1, Pleura, plasminogen activator inhibitor-1, Female, pleural fibrosis, residual pleura thickening, medicine.drug, Signal Transduction, Adult, tuberculous pleural fibrosis, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Tissue factor, Young Adult, Thrombin, In vivo, Plasminogen Activator Inhibitor 1, medicine, Animals, Humans, Tuberculosis, Receptor, PAR-1, Physical and Theoretical Chemistry, tuberculous pleural effusion, Molecular Biology, Aged, business.industry, Organic Chemistry, Mycobacterium tuberculosis, Fibrosis, In vitro, respiratory tract diseases, Fibronectin, Mice, Inbred C57BL, Pleural Effusion, Disease Models, Animal, pleural mesothelial cell, 030104 developmental biology, 030228 respiratory system, chemistry, lcsh:Biology (General), lcsh:QD1-999, biology.protein, Cancer research, business, Plasminogen activator, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898ef521247c15109b0023fa414edec8Test
https://www.mdpi.com/1422-0067/20/20/5076Test

5

RAGE Mediates Cholesterol Efflux Impairment in Macrophages Caused by Human Advanced Glycated Albumin

المؤلفون: Gurdip Daffu, Marisa Passarelli, Edna Regina Nakandakare, Ubiratan Fabres Machado, Xiaoping Shen, Adriana Machado-Lima, Maria Lúcia Corrêa-Giannella, Ann Marie Schmidt, Raquel López-Díez, R. S. Pinto, Rodrigo T. Iborra

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7265, p 7265 (2020)

مصطلحات موضوعية: Glycation End Products, Advanced, Male, 0301 basic medicine, endocrine system diseases, THP-1 Cells, Receptor for Advanced Glycation End Products, 030204 cardiovascular system & hematology, RAGE (receptor), lcsh:Chemistry, Mice, chemistry.chemical_compound, 0302 clinical medicine, Glycation, Null cell, RNA, Small Interfering, Receptor, lcsh:QH301-705.5, Spectroscopy, Mice, Knockout, advanced glycation end products, General Medicine, Transfection, RAGE, Computer Science Applications, NADPH Oxidase 4, diabetes mellitus, Female, lipids (amino acids, peptides, and proteins), Efflux, Adult, musculoskeletal diseases, medicine.medical_specialty, Serum Albumin, Human, Article, Catalysis, Cell Line, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, Triglycerides, Glycated Hemoglobin, Cholesterol, Macrophages, Cholesterol, HDL, Organic Chemistry, Albumin, NF-kappa B p50 Subunit, nutritional and metabolic diseases, cholesterol, Cholesterol, LDL, Fibroblasts, Janus Kinase 2, Mice, Inbred C57BL, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, chemistry, Case-Control Studies, atherosclerosis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589e04813a4b26c542aba72dead637e8Test
https://doi.org/10.3390/ijms21197265Test

6

Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer

المؤلفون: Romain R. Dehon, Serge Goldman, Koji Uchida, Florence Durieux, Akeila Bellahcene, Félicie Sherer, Justine Bellier, Olivier Peulen, Pierre Lovinfosse, Roland Hustinx, Philippe Delvenne, Noëlla Bletard, Marie-Julie Nokin, Pieter Demetter, Barbara Chiavarina, Vincent Castronovo, Laurine Verset, Andrei Turtoi

المساهمون: Université de Liège, Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Université libre de Bruxelles (ULB), University of Tokyo [Kashiwa Campus]

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 1; Pages: 213
International Journal of Molecular Sciences, Vol 18, Iss 1, p 213 (2017)
International Journal of Molecular Sciences, MDPI, 2017, 18 (1), pp.213. ⟨10.3390/ijms18010213⟩
International journal of molecular sciences, 18 (1

مصطلحات موضوعية: 0301 basic medicine, Colorectal cancer, [SDV]Life Sciences [q-bio], Carnosine, Informatique appliquée logiciel, lcsh:Chemistry, Cohort Studies, Physico-chimie générale, chemistry.chemical_compound, 0302 clinical medicine, Glycation, methylglyoxal, Medicine, Glycolysis, lcsh:QH301-705.5, Spectroscopy, Methylglyoxal, Lactoylglutathione Lyase, General Medicine, Middle Aged, Pyruvaldehyde, 3. Good health, Computer Science Applications, Biochemistry, 030220 oncology & carcinogenesis, Colorectal Neoplasms, Adult, colorectal cancer, Chimie inorganique, Catalysis, Article, glyoxalase 1, Inorganic Chemistry, 03 medical and health sciences, Fluorodeoxyglucose F18, Stress, Physiological, Cell Line, Tumor, Animals, Humans, Spectroscopie [état condense], Physical and Theoretical Chemistry, MG-adducts, 18F-Fluorodeoxyglucose (18F-FDG), Molecular Biology, Aged, Cell Proliferation, Neoplasm Staging, business.industry, Organic Chemistry, Biologie moléculaire, Cancer, Chimie théorique, medicine.disease, Chimie organique, Spectroscopie [électromagnétisme, optique, acoustique], 030104 developmental biology, Pyrimidines, Glyoxalase 1, lcsh:Biology (General), lcsh:QD1-999, chemistry, Anaerobic glycolysis, Positron-Emission Tomography, Cancer cell, Cancer research, Catalyses hétérogène et homogène, business, Chickens

وصف الملف: application/pdf; 1 full-text file(s): application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e9e6085cc94f9721368b057f2aae28Test
https://pubmed.ncbi.nlm.nih.gov/28117708Test

7

Discovery of a Highly Selective MC1R Agonists Pentapeptide to Be Used as a Skin Pigmentation Enhancer and with Potential Anti-Aging Properties

المؤلفون: Laurent Meeus, Rolf Schuetz, Remo Campiche, Marc Heidl, Dominik Imfeld, Eileen Jackson

المصدر: International Journal of Molecular Sciences
Volume 20
Issue 24

مصطلحات موضوعية: 0301 basic medicine, Photoaging, Skin Pigmentation, Human skin, medicine.disease_cause, Pentapeptide repeat, Melanin, Mice, 030207 dermatology & venereal diseases, 0302 clinical medicine, Drug Discovery, oxidative stress, pigmentation, Receptor, Spectroscopy, Membrane Glycoproteins, integumentary system, Monophenol Monooxygenase, Chemistry, General Medicine, Microphthalmia-associated transcription factor, Computer Science Applications, Cell biology, medicine.anatomical_structure, Melanocytes, Female, Oxidoreductases, Oligopeptides, Receptor, Melanocortin, Type 1, Adult, skin, NF-E2-Related Factor 2, Ultraviolet Rays, CHO Cells, Melanocyte, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, Cricetulus, MC1R, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, Microphthalmia-Associated Transcription Factor, molecular modeling, anti-aging, Organic Chemistry, medicine.disease, Skin Aging, 030104 developmental biology, peptides, Oxidative stress

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455e0611a260d9307a3486446739ae26Test
https://doi.org/10.3390/ijms20246143Test

8

Expression of the Antioxidative Enzyme Peroxiredoxin 2 in Multiple Sclerosis Lesions in Relation to Inflammation

المؤلفون: David Voigt, Andreas Junker, Wolfgang Brück, Tobias Derfuss, Uta Scheidt

المصدر: International Journal of Molecular Sciences, Vol 18, Iss 4, p 760 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 4; Pages: 760

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, Medizin, medicine.disease_cause, lcsh:Chemistry, NAD(P)H Dehydrogenase (Quinone), oxidative stress, Macrophage, peroxiredoxin 2 (PRDX2), lcsh:QH301-705.5, Cells, Cultured, Spectroscopy, Microglia, Reverse Transcriptase Polymerase Chain Reaction, General Medicine, Middle Aged, Immunohistochemistry, White Matter, 3. Good health, Computer Science Applications, multiple sclerosis (MS), medicine.anatomical_structure, Female, Autopsy, medicine.symptom, NAD(P)H quinone dehydrogenase 1 (NQO1), inflammation, Adult, medicine.medical_specialty, Multiple Sclerosis, Central nervous system, Inflammation, Context (language use), Peroxiredoxin 2, Biology, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, Aged, Multiple sclerosis, Organic Chemistry, Peroxiredoxins, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Astrocytes, Immunology, Oxidative stress

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9156ad3ec4261acc7417c23c54c85edTest
https://doi.org/10.3390/ijms18040760Test

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