التفاصيل البيبلوغرافية
| العنوان: |
Differentiating between benign and malignant adnexal lesions with contrast-enhanced transvaginal ultrasonography. |
| المؤلفون: |
Szymanski, Marek1,2, Socha, Maciej W.1,2, Kowalkowska, Magdalena E.1 mg.kowalkowska@gmail.com, Zielińska, Izabela B.3, Eljaszewicz, Andrzej4, Szymanski, Wieslaw1,2 |
| المصدر: |
International Journal of Gynecology & Obstetrics. Nov2015, Vol. 131 Issue 2, p147-151. 5p. |
| مصطلحات موضوعية: |
*ADNEXAL diseases, *TRANSVAGINAL ultrasonography, *OVARIAN cancer diagnosis, *UTERUS, *OVARIAN cancer, *DIAGNOSTIC examinations, *NEOVASCULARIZATION, *WOUNDS & injuries, *CANCER risk factors, *DIFFERENTIAL diagnosis, *LONGITUDINAL method, *OVARIAN tumors, *VAGINA, *COLOR Doppler ultrasonography, *PREDICTIVE tests, *CONTRAST media, *PATHOLOGIC neovascularization |
| مصطلحات جغرافية: |
POLAND |
| مستخلص: |
Objective: To analyze the relationship between contrast kinetics in tumorous vessels and lesion histologic type in an attempt to differentiate between malignant and benign disease.Methods: In a single-center prospective study, patients who had been referred for elective surgery because of a diagnosis of unilateral and/or bilateral adnexal masses were enrolled at Dr Jan Biziel University Hospital, Bydgoszcz, Poland, between January 2012 and September 2013. Participants underwent contrast-enhanced ultrasonography examination (CEUS). Contrast kinetics were obtained and compared with the neovascularization of the tumor. Accuracy, and positive and negative predictive values were calculated.Results: Among 160 enrolled patients, 84 underwent CEUS examination and 51 lesions were studied. Baseline and maximum color Doppler intensities were significantly higher in malignant than in benign tumors (P < 0.001 for both). Similarly, the absolute and relative increases in color Doppler intensity were significantly higher in malignant tumors (P < 0.001). The estimated positive predictive value was 97.1%, the negative predictive value was 100%, and the accuracy was 100%. Peak enhanced intensity of fractional color Doppler Area and area under the time-intensity curve (S-parameter) correlated significantly with the histology of the lesion (P < 0.001). Probability curves demonstrated that higher S-parameter values were correlated with a higher risk of malignancy.Conclusion: Transvaginal CEUS is a reliable and reproducible way to differentiate between benign and malignant adnexal lesions. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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