Cohort Profile: A population-based cohort to study non-motor symptoms in parkinsonism (EPIPARK)
| العنوان: | Cohort Profile: A population-based cohort to study non-motor symptoms in parkinsonism (EPIPARK) |
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| المؤلفون: | Heiner Raspe, Eva-Juliane Vollstedt, Elke Peters, Christine Klein, Anne Lorwin, Alexander Katalinic, Meike Kasten, Johann Hagenah, Julia Graf |
| المصدر: | International Journal of Epidemiology. 42:128-128k |
| بيانات النشر: | Oxford University Press (OUP), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Male, Sleep Wake Disorders, medicine.medical_specialty, Ultrasonography, Doppler, Transcranial, Epidemiology, Motor Activity, Neuropsychological Tests, Cohort Studies, Quality of life, Germany, Surveys and Questionnaires, Prevalence, medicine, Humans, Mass Screening, Somatization disorder, Psychiatry, Aged, Aged, 80 and over, Psychiatric Status Rating Scales, Depression, business.industry, Parkinsonism, Parkinson Disease, General Medicine, Middle Aged, medicine.disease, Comorbidity, Socioeconomic Factors, Case-Control Studies, Population Surveillance, Sensation Disorders, Cohort, Quality of Life, Anxiety, Female, Psychiatric interview, medicine.symptom, business, Somatization |
| الوصف: | Parkinson's disease is increasingly viewed as a complex disorder including a range of typical non-motor symptoms in addition to the cardinal motor signs. This cohort was set up in 2010 to investigate the specificity of non-motor symptoms for Parkinson's disease. For this, we included several control groups with decreasing contrast from Parkinson's disease patients. Group definitions ranged from healthy control subjects to those with suspected early motor signs of parkinsonism. Using a mailed questionnaire, we screened 5838 inhabitants of Lübeck, Germany, out of a target population of 10 000 citizens, enquiring about motor impairment, pain, quality of life, comorbidities, somatization and demographics. Based on this information, participants were assigned to screening groups, and selected participants were invited for in-person examination (n = 623). The examination included cognitive examinations, transcranial ultrasound, a brief psychiatric interview and a standardized motor examination that was used to assign examination groups. In addition, all participants answered questionnaires addressing depression, anxiety, sleep and quality of life. The first-year follow-up examination was performed either in person using the same protocol or via mailed questionnaires. This study is ongoing and publications are in preparation, but you may contact the first author (meike.kasten@neuro.uni-luebeck.de) with suggestions for collaboration or data requests. |
| تدمد: | 1464-3685 0300-5771 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1827163de4fd1cbeaba6d0bd42c7c3Test https://doi.org/10.1093/ije/dys202Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2a1827163de4fd1cbeaba6d0bd42c7c3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14643685 03005771 |
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