Health-Related Quality of Life in Weight Loss Interventions: Results from the OPTIWIN Trial
| العنوان: | Health-Related Quality of Life in Weight Loss Interventions: Results from the OPTIWIN Trial |
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| المؤلفون: | Jamy D. Ard, Sarah S. Cohen, Dan Roberto Luo, Agnieszka Marczewska, Walter J. Pories, Kristina H. Lewis, Sally L. Coburn, Amy E. Rothberg, Judy Loper, Livia Dainelli, Laura E. Matarese |
| المصدر: | International Journal of Environmental Research and Public Health, Vol 18, Iss 1785, p 1785 (2021) International Journal of Environmental Research and Public Health Volume 18 Issue 4 |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Health, Toxicology and Mutagenesis, Significant group, Psychological intervention, lcsh:Medicine, 030209 endocrinology & metabolism, Physical function, IWQOL-Lite, Health outcomes, WPAI-GH, Article, 03 medical and health sciences, 0302 clinical medicine, Weight loss, Surveys and Questionnaires, Weight Loss, medicine, Humans, Obesity, 030212 general & internal medicine, Health related quality of life, business.industry, lcsh:R, Body Weight, Public Health, Environmental and Occupational Health, medicine.disease, humanities, weight loss interventions, Weight loss interventions, Quality of Life, Physical therapy, health-related quality-of-life, medicine.symptom, business |
| الوصف: | Obesity is highly prevalent and associated with several adverse outcomes including health-related quality-of-life (HRQoL), work productivity, and activity impairment. The objective of this study is to examine group differences in HRQoL and labor-related health outcomes among participants in the OPTIWIN program, which compared the effectiveness of two intensive behavioral weight loss interventions. Participants (n = 273) were randomized to OPTIFAST®(OP) or food-based (FB) dietary interventions for 52 weeks. HRQoL and labor-related health outcomes were measured at baseline, week 26, and week 52, using two questionnaires. At baseline, there were no differences between groups on the Impact of Weight on Quality-of-Life Questionnaire (IWQOL-Lite). At week 26, the OP group had statistically significant differences towards better HRQoL for Physical Function, Self-Esteem, and the total score compared with the FB group. At week 52, the OP group showed better HRQoL in the total score (p = 0.0012) and in all but one domain. Moreover, the adjusted change-from-baseline normalized total score at week 52 was −5.9 points (p = 0.0001). Finally, the mean IWQOL-Lite normalized score showed that HRQoL improves by 0.4442 units (p < 0.0001) per kg lost, and that greater weight reduction was positively associated with better HRQoL. No statistically significant group differences were found with the Work Productivity and Activity Impairment (General Health) (WPAI-GH) Questionnaire. HRQoL improves with highly intensive, well-structured weight loss interventions. Greater weight loss lead to larger improvements. The lack of negative effect on productivity and activity suggests that these interventions may be compatible with an active work lifestyle. |
| وصف الملف: | application/pdf |
| تدمد: | 1660-4601 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8905989bf496f48358ffe181342de1Test https://doi.org/10.3390/ijerph18041785Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3a8905989bf496f48358ffe181342de1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16604601 |
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