Broadening and Enhancing Bacteriocins Activities by Association with Bioactive Substances
| العنوان: | Broadening and Enhancing Bacteriocins Activities by Association with Bioactive Substances |
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| المؤلفون: | Djamel Drider, Hassan Zgheib, Yanath Belguesmia |
| المساهمون: | Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 (IEMN), Centrale Lille-Institut supérieur de l'électronique et du numérique (ISEN)-Université de Valenciennes et du Hainaut-Cambrésis (UVHC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF), Transfrontalière BioEcoAgro (Transfrontalière BioEcoAgro), Université d'Artois (UA)-Université de Liège-Université de Picardie Jules Verne (UPJV)-Université du Littoral Côte d'Opale (ULCO)-Université de Lille-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), This research was funded by La Région des Hauts-de-France, through ALIBIOTECH CPER/FEDER 2016/2021., Transfrontalière BioEcoAgro - UMR 1158 (BioEcoAgro), Université d'Artois (UA)-Université de Liège-Université de Picardie Jules Verne (UPJV)-Université du Littoral Côte d'Opale (ULCO)-Université de Lille-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-JUNIA (JUNIA), Université catholique de Lille (UCL)-Université catholique de Lille (UCL) |
| المصدر: | International Journal of Environmental Research and Public Health International Journal of Environmental Research and Public Health, Vol 17, Iss 7835, p 7835 (2020) International Journal of Environmental Research and Public Health, MDPI, 2020, 17 (21), pp.7835. ⟨10.3390/ijerph17217835⟩ International Journal of Environmental Research and Public Health, 2020, 17 (21), pp.7835. ⟨10.3390/ijerph17217835⟩ |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.drug_class, Health, Toxicology and Mutagenesis, Bioactive molecules, Antimicrobial peptides, Antibiotics, lcsh:Medicine, phages, Review, anticancer, antibiotics, 03 medical and health sciences, [SPI]Engineering Sciences [physics], Antibiotic resistance, Bacteriocin, Anti-Infective Agents, Bacteriocins, bacteriocin, synergism, medicine, essential oils, 030304 developmental biology, 0303 health sciences, 030306 microbiology, Chemistry, antibiofilm, lcsh:R, Public Health, Environmental and Occupational Health, food and beverages, Antimicrobial, antiviral, 3. Good health, Anti-Bacterial Agents, Biochemistry, nanoparticles, Enzymatic degradation |
| الوصف: | International audience; Bacteriocins are antimicrobial peptides some of which are endowed with antiviral, anticancer and antibiofilm properties. These properties could be improved through synergistic interactions of these bacteriocins with other bioactive molecules such as antibiotics, phages, nanoparticles and essential oils. A number of studies are steadily reporting the effects of these combinations as new and potential therapeutic strategies in the future, as they may offer many incentives over existing therapies. In particular, bacteriocins can benefit from combination with nanoparticles which can improve their stability and solubility, and protect them from enzymatic degradation, reduce their interactions with other molecules and improve their bioavailability. Furthermore, the combination of bacteriocins with other antimicrobials is foreseen as a way to reduce the development of antibiotic resistance due to the involvement of several modes of action. Another relevant advantage of these synergistic combinations is that it decreases the concentration of each antimicrobial component, thereby reducing their side effects such as their toxicity. In addition, combination can extend the utility of bacteriocins as antiviral or anticancer agents. Thus, in this review, we report and discuss the synergistic effects of bacteriocin combinations as medicines, and also for other diverse applications including, antiviral, antispoilage, anticancer and antibiofilms. |
| تدمد: | 1660-4601 1661-7827 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4818c6a571a95854d9f76d897a7bf1Test https://pubmed.ncbi.nlm.nih.gov/33114656Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....de4818c6a571a95854d9f76d897a7bf1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16604601 16617827 |
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