Dietary total antioxidant capacity and gastric cancer risk in the European prospective investigation into cancer and nutrition study
| العنوان: | Dietary total antioxidant capacity and gastric cancer risk in the European prospective investigation into cancer and nutrition study |
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| المؤلفون: | Antonia Trichopoulou, Leila Lujan-Barroso, Suzanne M. Jeurnink, Petra H.M. Peeters, Françoise Clavel-Chapelon, Domenico Palli, Sophie Morois, Roger Stenling, Christina C. Dahm, Fränzel J.B. Van Duijnhoven, Timothy J. Key, Majken K. Jensen, Christina Bamia, Anja Olsen, Peter Wallström, Eiliv Lund, José Ramón Quirós, Esther Molina-Montes, Aurelio Barricarte, José María Huerta Castaño, Rosario Tumino, Manuela M. Bergmann, Nicholas J. Wareham, Mauro Serafini, Carmen Navarro, Rudolf Kaaks, Naomi E. Allen, Pilar Amiano, Paula Jakszyn, Fátima Carneiro, Kay-Tee Khaw, Kim Overvad, Marie-Christine Boutron-Ruault, Sara Grioni, Salvatore Panico, Björn Lindkvist, Elisabeth Valanou, Mattijs E. Numans, Dominique S. Michaud, Carlotta Sacerdote, Sara Regnér, Sabina Rinaldi, Carlos González, Antonio Agudo, Annekatrin Lukanova, H. Bas Bueno-de-Mesquita, Traci Mouw, Ingegerd Johansson, Anne Tjønneland, Elio Riboli, Mazda Jenab, Heiner Boeing |
| المصدر: | Serafini, M, Jakszyn, P, Luján-Barroso, L, Agudo, A, Bueno-de-Mesquita, H B, van Duijnhoven, F J B, Jenab, M, Navarro, C, Palli, D, Boeing, H, Wallström, P, Regnér, S, Numans, M E, Carneiro, F, Boutron-Ruault, M-C, Clavel-Chapelon, F, Morois, S, Grioni, S, Panico, S, Tumino, R, Sacerdote, C, Quirós, J R, Molina-Montes, E, Huerta Castaño, J M, Barricarte, A, Amiano, P, Khaw, K-T, Wareham, N, Allen, N E, Key, T J, Jeurnink, S M, Peeters, P H, Bamia, C, Valanou, E, Trichopoulou, A, Kaaks, R, Lukanova, A, Bergmann, M M, Lindkvist, B, Stenling, R, Johansson, I, Dahm, C C, Overvad, K, Jensen, M, Olsen, A, Tjonneland, A, Lund, E, Rinaldi, S, Michaud, D, Mouw, T, Riboli, E & González, C A 2012, ' Dietary total antioxidant capacity and gastric cancer risk in the european prospective investigation into cancer and nutrition study ', International Journal of Cancer, vol. 131, no. 4, pp. E544-54 . https://doi.org/10.1002/ijc.27347Test |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Male, Cancer Research, medicine.medical_specialty, Antioxidant, medicine.medical_treatment, Antioxidant potential, Antioxidants, Risk Factors, Stomach Neoplasms, Medicine, Humans, Food science, Prospective Studies, Stomach cancer, Prospective cohort study, Aged, business.industry, Cancer, Middle Aged, medicine.disease, Surgery, European Prospective Investigation into Cancer and Nutrition, Diet, Europe, Antioxidant capacity, Oncology, Female, business, Cancer risk |
| الوصف: | A high intake of dietary antioxidant compounds has been hypothesized to be an appropriate strategy to reduce gastric cancer (GC) development. We investigated the effect of dietary total antioxidant capacity (TAC) in relation to GC in the European Prospective Investigation into Cancer (EPIC) study including 23 centers in 10 European countries. A total of 521,457 subjects (153,447 men) aged mostly 35-70 years old, were recruited largely between 1992 and 1998. Ferric reducing antioxidant potential (FRAP) and total radical-trapping antioxidant parameter (TRAP), measuring reducing and chain-breaking antioxidant capacity were used to measure dietary TAC from plant foods. Dietary antioxidant intake is associated with a reduction in the risk of GC for both FRAP (adjusted HR 0.66; 95%CI (0.46-0.95) and TRAP (adjusted HR 0.61; 95%CI (0.43-0.87) (highest vs. lowest quintile). The association was observed for both cardia and noncardia cancers. A clear effect was observed in smokers with a significant reduction in GC risk for the fifth quintile of intake for both assays (highest vs. lowest quintile: adjusted HR 0.41; 95%CI (0.22-0.76) p for trend |
| اللغة: | English |
| تدمد: | 1097-0215 0020-7136 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e4c0c0d86ae625233dd95ce6d2e228Test http://ora.ox.ac.uk/objects/uuid:3f58fe26-e1fa-4f57-a1e8-f585e4eb75b8Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....27e4c0c0d86ae625233dd95ce6d2e228 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10970215 00207136 |
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