دورية أكاديمية

Depressive symptoms, functional measures and long-term outcomes of high-risk ST-elevated myocardial infarction patients treated by primary angioplasty.

التفاصيل البيبلوغرافية
العنوان: Depressive symptoms, functional measures and long-term outcomes of high-risk ST-elevated myocardial infarction patients treated by primary angioplasty.
المؤلفون: Compostella, Leonida, Lorenzi, Sonia, Russo, Nicola, Setzu, Tiziana, Compostella, Caterina, Vettore, Elia, Isabella, Giambattista, Tarantini, Giuseppe, Iliceto, Sabino, Bellotto, Fabio
المصدر: Internal & Emergency Medicine; Feb2017, Vol. 12 Issue 1, p31-43, 13p
مصطلحات موضوعية: ANGIOPLASTY, MENTAL depression, PROGNOSIS, PSYCHOMETRICS, RISK assessment, SELF-evaluation, TIME, RETROSPECTIVE studies, REHABILITATION, STANDARDS, PSYCHOLOGY, EQUIPMENT & supplies
مستخلص: The presence of major depressive symptoms is usually considered a negative long-term prognostic factor after an acute myocardial infarction (AMI); however, most of the supporting research was conducted before the era of immediate reperfusion by percutaneous coronary intervention. The aims of this study are to evaluate if depression still retains long-term prognostic significance in our era of immediate coronary reperfusion, and to study possible correlations with clinical parameters of physical performance. In 184 patients with recent ST-elevated AMI (STEMI), treated by immediate reperfusion, moderate or severe depressive symptoms (evaluated by Beck Depression Inventory version I) were present in 10 % of cases. Physical performance was evaluated by two 6-min walk tests and by a symptom-limited cardiopulmonary exercise test: somatic/affective (but not cognitive/affective) symptoms of depression and perceived quality of life (evaluated by the EuroQoL questionnaire) are worse in patients with lower levels of physical performance. Follow-up was performed after a median of 29 months by means of telephone interviews; 32 major adverse cardiovascular events (MACE) occurred. The presence of three vessels disease and low left ventricle ejection fraction are correlated with a greater incidence of MACE; only somatic/affective (but not cognitive/affective) symptoms of depression correlate with long-term outcomes. In patients with recent STEMI treated by immediate reperfusion, somatic/affective but not cognitive/affective symptoms of depression show prognostic value on long-term MACE. Depression symptoms are not predictors "per se" of adverse prognosis, but seem to express an underlying worse cardiac efficiency, clinically reflected by poorer physical performance. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:18280447
DOI:10.1007/s11739-016-1504-9