دورية
Improving the glial differentiation of human Schwann-like adipose-derived stem cells with graphene oxide substrates
| العنوان: | Improving the glial differentiation of human Schwann-like adipose-derived stem cells with graphene oxide substrates |
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| المؤلفون: | Verre, Andrea Francesco, Faroni, Alessandro, Iliut, Maria, Silva, Claudio, Muryn, Cristopher, Reid, Adam J., Vijayaraghavan, Aravind |
| المصدر: | Interface Focus; June 2018, Vol. 8 Issue: 3 |
| مستخلص: | There is urgent need to improve the clinical outcome of peripheral nerve injury. Many efforts are directed towards the fabrication of bioengineered conduits, which could deliver stem cells to the site of injury to promote and guide peripheral nerve regeneration. The aim of this study is to assess whether graphene and related nanomaterials can be useful in the fabrication of such conduits. A comparison is made between graphene oxide (GO) and reduced GO substrates. Our results show that the graphene substrates are highly biocompatible, and the reduced GO substrates are more effective in increasing the gene expression of the biomolecules involved in the regeneration process compared to the other substrates studied. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 20428898 20428901 |
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| DOI: | 10.1098/rsfs.2018.0002 |