Overton's rule overturned.

التفاصيل البيبلوغرافية
العنوان: Overton's rule overturned.
المصدر: Inpharma Weekly. 8/30/2008, Issue 1653, p11-11. 1/4p.
مصطلحات موضوعية: *ULTRAMICROELECTRODES, *ACIDS, *DIFFUSION, *LIPIDS, *MEMBRANE lipids, *CELL membranes, *BIOLOGICAL transport
مستخلص: The article reports on a study on the invalidation of the Overton's rule. It references a study conducted by a team from the University of Warwick in England led by professor Patrick Unwin and posted on http://www.eurekalertTest. org on August 25, 2008. Under the study, an ultramicroelectrode was used in generating a range of acids that are able to diffuse easily into a cell. Results of the study show the opposite of the Overton's rule in which acids that easily dissolves in a lipid tend to transport slower across the membrane.
قاعدة البيانات: Academic Search Index
الوصف
تدمد:11738324
DOI:10.2165/00128413-200816530-00030