دورية
Risk Factors for Infection and Molecular Typing in Patients in the Intensive Care Unit Colonized with Nosocomial Enterobacter Aerogenes
| العنوان: | Risk Factors for Infection and Molecular Typing in Patients in the Intensive Care Unit Colonized with Nosocomial Enterobacter Aerogenes |
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| المؤلفون: | Piagnerelli, Michael, Carlier, Eric, Deplano, Ariane, Lejeune, Philippe, Govaerts, Danielle |
| المصدر: | Infection Control & Hospital Epidemiology; August 2002, Vol. 23 Issue: 8 p452-456, 5p |
| مستخلص: | Objectives:To determine the frequency of colonization by Enterobacter aerogenesin patients in the intensive care unit (ICU) for more than 48 hours and to evaluate the risk factors for infection in patients colonized by this bacteria.Design:An 8-month prospective study.Setting:A 12-bed medical–surgical ICU in a 450-bed, university-affiliated, tertiary-care hospital in Belgium.Method:Pulsed-field gel electrophoresis was used to determine the genotypes of E. aerogenesisolates.Results:We observed two major clones of E. aerogenesin the ICU. Interestingly, 87.5% of infected patients had the same genomic profile for colonization and infection. Risk factors for infection in this particular population included younger age, prolonged hospital stay, mechanical ventilation, and bronchoscopy.Conclusions:Colonization is a major prerequisite for infection. The identification of risk factors for infection in colonized patients can optimize the quality of treatment in the ICU. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 0899823X 15596834 |
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| DOI: | 10.1086/502084 |