دورية أكاديمية

Dendritic cells play a role in host susceptibility to Cryptosporidium parvum infection.

التفاصيل البيبلوغرافية
العنوان: Dendritic cells play a role in host susceptibility to Cryptosporidium parvum infection.
المؤلفون: Bedi, Brahmchetna1,2, McNair, Nina N.2, Mead, Jan R.1,2 jmead@emory.edu
المصدر: Immunology Letters. Mar2014, Vol. 158 Issue 1/2, p42-51. 10p.
مصطلحات موضوعية: *DENDRITIC cells, *CRYPTOSPORIDIOSIS, *DISEASE susceptibility, *SPOROZOITES, *T cells, *CELL culture
مستخلص: Highlights: [•] Depletion of DCs in vivo increases susceptibility to Cryptosporidium parvum infection. [•] Adoptive transfer of stimulated DCs reduces C. parvum infection levels. [•] Reduction in infection correlates to an increase in IFN-γ in T cell. [•] DCs pulsed with sporozoites and co-cultured with CD4+ and CD8+ T cells produced higher IFN-γ levels. [Copyright &y& Elsevier]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:01652478
DOI:10.1016/j.imlet.2013.11.015