دورية أكاديمية
Conservation of the three-dimensional structure in non-homologous or unrelated proteins
| العنوان: | Conservation of the three-dimensional structure in non-homologous or unrelated proteins |
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| المؤلفون: | Sousounis Konstantinos, Haney Carl E, Cao Jin, Sunchu Bharath, Tsonis Panagiotis A |
| المصدر: | Human Genomics, Vol 6, Iss 1, p 10 (2012) |
| بيانات النشر: | BMC, 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Medicine LCC:Genetics |
| مصطلحات موضوعية: | 3D protein structure, Conserved motifs, Unrelated proteins, Medicine, Genetics, QH426-470 |
| الوصف: | Abstract In this review, we examine examples of conservation of protein structural motifs in unrelated or non-homologous proteins. For this, we have selected three DNA-binding motifs: the histone fold, the helix-turn-helix motif, and the zinc finger, as well as the globin-like fold. We show that indeed similar structures exist in unrelated proteins, strengthening the concept that three-dimensional conservation might be more important than the primary amino acid sequence. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1479-7364 |
| العلاقة: | http://www.humgenomics.com/content/6/1/10Test; https://doaj.org/toc/1479-7364Test |
| DOI: | 10.1186/1479-7364-6-10 |
| الوصول الحر: | https://doaj.org/article/1b6d1b33e8cb4f19a6afc82feb3ed117Test |
| رقم الانضمام: | edsdoj.1b6d1b33e8cb4f19a6afc82feb3ed117 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14797364 |
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| DOI: | 10.1186/1479-7364-6-10 |