Classification of human enteric neurons
| العنوان: | Classification of human enteric neurons |
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| المؤلفون: | Brehmer, Axel |
| المصدر: | Histochemistry and Cell Biology |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Histology, Stach, Review, Neuropathology, Biology, Dogiel, 03 medical and health sciences, Functional diversity, 0302 clinical medicine, Neurochemical, Afferent, Humans, Neuroanatomical terminology, ddc:610, Molecular Biology, Neurons, Cell Biology, Immunohistochemistry, Medical Laboratory Technology, 030104 developmental biology, nervous system, Enteric nervous system, Neuroscience, 030217 neurology & neurosurgery |
| الوصف: | Major advances in our understanding of the functional heterogeneity of enteric neurons are driven by the application of newly developed, innovative methods. In contrast to this progress, both animal and human enteric neurons are usually divided into only two morphological subpopulations, “Dogiel type II” neurons (with several long processes) and “Dogiel type I” neurons (with several short processes). This implies no more than the distinction of intrinsic primary afferent from all other enteric neurons. The well-known chemical and functional diversity of enteric neurons is not reflected by this restrictive dichotomy of morphological data. Recent structural investigations of human enteric neurons were performed by different groups which mainly used two methodical approaches, namely detecting the architecture of their processes and target-specific tracing of their axonal courses. Both methods were combined with multiple immunohistochemistry in order to decipher neurochemical codes. This review integrates these morphological and immunohistological data and presents a classification of human enteric neurons which we believe is not yet complete but provides an essential foundation for the further development of human gastrointestinal neuropathology. |
| وصف الملف: | application/pdf |
| تدمد: | 1432-119X 0948-6143 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031b288e53481aaa3514ad2a0c90afc5Test https://doi.org/10.1007/s00418-021-02002-yTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....031b288e53481aaa3514ad2a0c90afc5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1432119X 09486143 |
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