ASH evidence-based guidelines: should asymptomatic patients with antiphospholipid antibodies receive primary prophylaxis to prevent thrombosis?

التفاصيل البيبلوغرافية
العنوان: ASH evidence-based guidelines: should asymptomatic patients with antiphospholipid antibodies receive primary prophylaxis to prevent thrombosis?
المؤلفون: Metjian, Ara, Lim, Wendy
المصدر: Hematology; January 2009, Vol. 2009 Issue: 1 p247-249, 3p
مستخلص: A 35-year-old female presents with a prolonged activated partial thromboplastin time (aPTT) on routine testing, which is found to be due to a lupus anticoagulant. She has no medical issues, no personal or family history of thrombosis, no history of pregnancy loss, and no symptoms suggestive of an underlying rheumatologic disorder. She is a non-smoker and does not take oral contraceptives. You are asked to provide recommendations regarding the need for primary thromboprophylaxis. As you begin your literature search, you formulate the following clinical question: “In asymptomatic patients with antiphospholipid antibodies, does primary prophylaxis prevent thrombotic complications?”
قاعدة البيانات: Supplemental Index
الوصف
تدمد:15204391
15204383
DOI:10.1182/asheducation-2009.1.247