دورية أكاديمية
Intravesical Instillations of Hyaluronic Acid as First-Line Treatment in Patients with Interstitial Cystitis/Bladder Pain Syndrome: Use, Efficacy and Effects on Quality of Life.
| العنوان: | Intravesical Instillations of Hyaluronic Acid as First-Line Treatment in Patients with Interstitial Cystitis/Bladder Pain Syndrome: Use, Efficacy and Effects on Quality of Life. |
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| المؤلفون: | Plotti, Francesco, Cundari, Gianna Barbara, Ficarola, Fernando, Terranova, Corrado, De Cicco Nardone, Carlo, Montera, Roberto, Luvero, Daniela, Guzzo, Federica, Silvagni, Adele, Ferrari, Amerigo, Caserta, Donatella, Angioli, Roberto |
| المصدر: | Healthcare (Basel) ; ISSN:2227-9032 ; Volume:12 ; Issue:12 |
| بيانات النشر: | MDPI |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | bladder pain syndrome, glycosaminoglycans, hyaluronic acid, interstitial cystitis |
| الوصف: | The efficacy of hyaluronic acid instillations as therapy for patients with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) has been demonstrated in some clinical studies, with response rates up to 70%. The aim of the study is to investigate the change in symptoms and quality of life in female patients with IC/BPS after intravesical instillations of hyaluronic acid used as first-line treatment. A retrospective single-center cohort study was conducted. Female patients, whose symptoms were compatible with the diagnosis of IC/BPS as defined by the International Continence Society, were treated with a variable number of intravesical instillations of a hyaluronic acid-based drug. Three validated questionnaires were administered by telephone to all patients, before the beginning of the treatment and 6 months after the last administration of the drug. A total of 50 patients with symptoms compatible with the diagnosis of IC/BPS were included in the study. The median number of instillations performed is 4. For all questionnaires, the median value was significantly reduced following treatment with intravesical instillations (p = 0.000). The present study has shown that intravesical hyaluronic acid treatment results in both statistically and clinically significant symptomatic improvement, thereby improving the quality of life of patients with IC/BPS. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.3390/healthcare12121190Test; https://pubmed.ncbi.nlm.nih.gov/38921303Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11203325Test/ |
| DOI: | 10.3390/healthcare12121190 |
| الإتاحة: | https://doi.org/10.3390/healthcare12121190Test https://pubmed.ncbi.nlm.nih.gov/38921303Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11203325Test/ |
| رقم الانضمام: | edsbas.824DAEAE |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/healthcare12121190 |
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