دورية أكاديمية
Progress on contact lens for extended ophthalmic drug delivery
| العنوان: | Progress on contact lens for extended ophthalmic drug delivery |
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| المؤلفون: | Zhao Wang, Qing Lin, Xiao-Juan Zhang, Xiao-Mei Wang, Ling-Yun Hao |
| المصدر: | Guoji Yanke Zazhi, Vol 22, Iss 10, Pp 1647-1651 (2022) |
| بيانات النشر: | Press of International Journal of Ophthalmology (IJO PRESS) |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | contact lens, drug delivery, sustained drug release, vitamin e, molecular imprinting technology, nanoparticles, Ophthalmology, RE1-994 |
| الوصف: | Conventional eye treatment formulation such as eye drops has shortcomings including low drug utilization and poor patient compliance. The contact lens(CL), well-known as visual correction lens, is considered to be a more promising ophthalmic drug delivery vehicle owing to its good biocompatibility, long-term wearing comfort, prolonged drug residence time and improved bioavailability. In order to improve the drug loading efficiency and prolong the release time, researchers have developed a variety of strategies to modify traditional CL, including the introduction of vitamin E molecular barrier, application of molecular imprinting technology of CL, increasing interactions between the drug and polymer matrix by introducing special genes, and incorporation of nanocarriers or drug-loaded polymer films. In this paper, the preparation methods and pros and cons of drug-loaded CL are reviewed. At last, the existing problems and future developments of CL as ophthalmic drug delivery carrier are briefly discussed. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1672-5123 |
| العلاقة: | http://ies.ijo.cn/cn_publish/2022/10/202210010.pdfTest; https://doaj.org/toc/1672-5123Test; https://doaj.org/article/320d3fa2f79e47aeb198fa2f325675b8Test |
| DOI: | 10.3980/j.issn.1672-5123.2022.10.10 |
| الإتاحة: | https://doi.org/10.3980/j.issn.1672-5123.2022.10.10Test https://doaj.org/article/320d3fa2f79e47aeb198fa2f325675b8Test |
| رقم الانضمام: | edsbas.7A765335 |
| قاعدة البيانات: | BASE |
| تدمد: | 16725123 |
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| DOI: | 10.3980/j.issn.1672-5123.2022.10.10 |