التفاصيل البيبلوغرافية
| العنوان: |
Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study) |
| المؤلفون: |
Cieuta-Walti, Cécile, Cuenca-Royo, Aida, Langohr, Klaus, Rakic, Claire, López-Vílchez, MaÁngeles, Lirio, Julián, González-Lamuño Leguina, Domingo, González, Teresa Bermejo, García, Jordi García, Roure, Maria Rimblas, Aldea-Perona, Ana, Forcano, Laura, Gomis-Gonzalez, Maria, Cés, Sebastià Videla, Lacaille, Florence, Ravel, Aimé, Mircher, Clotilde, Walti, Hervé, Janel, Nathalie, Dairou, Julien, Lévy, Marilyne, Durand, Sophie, Dierssen, Mara, Sacco, Silvia, Fornell, Rafael de la Torre, Guerrico, Ion Álvarez, Goday, Albert, Llop, Cristina, Mateus, Julián, Matilla, Iris, Esther, Menoyo, Hernández-Ligero, Lorena, Pérez, Marta, Pizarro, Neus, Principe, Alessandro, Cortesi, Anna, Gomez, Alba, Paredes, Noelia, Gomez, Cristina, Graell, Montserrat, López, Pilar, Lozano, Rosario, Medrano, Constancio, Andrade-Navarro, Maria Teresa, Daza, Gema, Garcia, Sandra, Gayán, Ma Luisa, Guerra-Colorado, Cristina, Luna, Beatriz, Maya, Enriqueta, Millan, Delia, Reina, Macarena, Amigo, María Teresa, Fernández, José Luís, García-Martínez, María, Pérez-Poyato, María del Socorro, Pozueta, Ana, Tato, Emma, Viadero, María Teresa, Akkaya, Magnolia, Falquero, Ségolène, Gambarini, Alicia, Akkaya, Magnolia, Falquero, Ségolène, Gambarini, Alicia |
| المصدر: |
Genetics in Medicine; October 2022, Vol. 24 Issue: 10 p2004-2013, 10p |
| مستخلص: |
Although some caregivers are using epigallocatechin gallate (EGCG) off label in hopes of improving cognition in young adults with Down syndrome (DS), nothing is known about its safety, tolerability, and efficacy in the DS pediatric population. We aimed to evaluate safety and tolerability of a dietary supplement containing EGCG and if EGCG improves cognitive and functional performance. |
| قاعدة البيانات: |
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