التفاصيل البيبلوغرافية
| العنوان: |
Overview of Gene Special Issue "Genetic Conditions Affecting the Skeleton: Congenital, Idiopathic Scoliosis and Arthrogryposis". |
| المؤلفون: |
Giampietro, Philip F., Hadley-Miller, Nancy, Raggio, Cathy L. |
| المصدر: |
Genes; Jul2022, Vol. 13 Issue 7, p1194-1194, 3p |
| مصطلحات موضوعية: |
SCOLIOSIS, ARTHROGRYPOSIS, WNT signal transduction, ADOLESCENT idiopathic scoliosis, GENES, SKELETON |
| مستخلص: |
Genetic loci in muscle developmental genes ( I LBX1 i and I BNC2 i ) and extracellular matrix genes ( I FBN1 i ) have been identified as potential predisposition genes for IS. In this Special Issue of I Genes i entitled "Genetic Conditions Affecting the Skeleton: Congenital, Idiopathic Scoliosis and Arthrogryposis", evidence is presented which suggests that congenital, idiopathic scoliosis, and arthrogryposis share similar overlapping, but also distinct etiopathogenic mechanisms, including connective tissue and neuromuscular mechanisms. GWAS studies have confirmed the complexity of IS and the existence of low-penetrance genes associated with IS. [Extracted from the article] |
|
Copyright of Genes is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder