The Telomeric Complex and Metabolic Disease
| العنوان: | The Telomeric Complex and Metabolic Disease |
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| المؤلفون: | Fozia Shaheen, Henrik Oster, Henriette Kirchner, Sebastian M. Schmid, Hendrik Lehnert, Hannes Kalscheuer |
| المصدر: | Genes Genes, Vol 8, Iss 7, p 176 (2017) |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, Genetics, lcsh:QH426-470, diabetes, Nutrient sensing, Review, leucocyte telomere length, 030204 cardiovascular system & hematology, Biology, Bioinformatics, metabolic diseases, Telomere, 03 medical and health sciences, lcsh:Genetics, 030104 developmental biology, 0302 clinical medicine, obesity telomere shortening, Metabolic disease, Genetics (clinical) |
| الوصف: | The attrition of telomeres is believed to be a key event not only in mammalian aging, but also in disturbed nutrient sensing, which could lead to numerous metabolic dysfunctions. The current debate focuses mainly on the question whether telomere shortening, e.g., as a heritable trait, may act as a cause or rather represents a consequence of such chronic diseases. This review discusses the damaging events that ultimately may lead or contribute to telomere shortening and can be associated with metabolic diseases. |
| تدمد: | 2073-4425 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873a189aa810472c7324bea8dc6d491aTest https://pubmed.ncbi.nlm.nih.gov/28686177Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....873a189aa810472c7324bea8dc6d491a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20734425 |
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