Does auxiliary heterotopic liver transplantation reverse hypersplenism and portal hypertension?

التفاصيل البيبلوغرافية
العنوان: Does auxiliary heterotopic liver transplantation reverse hypersplenism and portal hypertension?
المؤلفون: Borel Rinkes, Inne H.M., Van Der Hoop, Arthur Gerritsen, Hesselink, Erik J., Metselaar, Herold, De Rave, Sjoerd, Zonderland, Harmine M., Schalm, Solko W., Terpstra, Onno T.
المصدر: Gastroenterology; April 1991, Vol. 100 Issue: 4 p1126-1128, 3p
مستخلص: In this study, performed to assess the effect of auxiliary heterotopic liver transplantation on portal hypertension and hypersplenism, eight patients with chronic liver disease who underwent the procedure and had functioning grafts for at least 6 months were analyzed. The transplantation resulted in (a) normalization of platelet and leukocyte counts, (b) reduction of splenomegaly by 20% ± 3% (P< 0.02), (c) disappearance of ascites, and (d) diminution of esophageal varices in all patients. Intraoperatively, the mean portacaval pressure gradient decreased with 54% ± 7% after recirculation of the graft (P< 0.05). In conclusion, a functioning auxiliary heterotopic liver graft decompresses portal hypertension and reverses hypersplenism.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00165085
15280012
DOI:10.1016/0016-5085(91)90293-T