British Red Squirrels Remain the Only Known Wild Rodent Host for Leprosy Bacilli
| العنوان: | British Red Squirrels Remain the Only Known Wild Rodent Host for Leprosy Bacilli |
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| المؤلفون: | Anna-Katarina Schilling, Charlotte Avanzi, Rainer G. Ulrich, Philippe Busso, Benoit Pisanu, Nicola Ferrari, Claudia Romeo, Maria Vittoria Mazzamuto, Joyce McLuckie, Craig M. Shuttleworth, Jorge Del-Pozo, Peter W. W. Lurz, Wendy G. Escalante-Fuentes, Jorge Ocampo-Candiani, Lucio Vera-Cabrera, Karen Stevenson, Jean-Louis Chapuis, Anna L. Meredith, Stewart T. Cole |
| المصدر: | Schilling, A, Avanzi, C, Ulrich, R G, Busson, P, Pisanu, B, Ferrari, N, Romeo, C, Mazzamuto, M V, McLuckie, J, Shuttleworth, C M, Del-Pozo, J, Lurz, P, Escalante-Fuentes, W G, Ocampo-Candiani, J, Vera-Cabrera, L, Stevenson, K, Chapuis, J-L, Meredith, A & Cole, S T 2019, ' British Red Squirrels Remain the Only Known Wild Rodent Host for Leprosy Bacilli ', Frontiers in Veterinary Science . https://doi.org/10.3389/fvets.2019.00008Test Frontiers in Veterinary Science Frontiers in Veterinary Science, Vol 6 (2019) |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Rodent, 040301 veterinary sciences, animal diseases, white-throated woodrats, Mycobacteriumlepromatosis, Zoology, population, medicine.disease_cause, behavioral disciplines and activities, mycobacterium lepromatosis, 0403 veterinary science, 03 medical and health sciences, pcr, biology.animal, medicine, infections, mycobacterium leprae, armadillo, Ground squirrel, Callosciurus erythraeus, 030304 developmental biology, Sciurus, Original Research, Mycobacterium lepromatosis, naturally acquired leprosy, 0303 health sciences, lcsh:Veterinary medicine, Sciurus carolinensis, General Veterinary, biology, squirrels, 04 agricultural and veterinary sciences, biology.organism_classification, medicine.disease, Siberian chipmunk, 3. Good health, PCR, Mycobacteriumleprae, lcsh:SF600-1100, Veterinary Science, Leprosy, white-throatedwoodrats, leprosy, psychological phenomena and processes |
| الوصف: | Eurasian red squirrels (Sciurus vulgaris) in the British Isles are the most recently discovered animal reservoir for the leprosy bacteria Mycobacterium leprae and Mycobacterium lepromatosis. Initial data suggest that prevalence of leprosy infection is variable and often low in different squirrel populations. Nothing is known about the presence of leprosy bacilli in other wild squirrel species despite two others (Siberian chipmunk [Tamias sibiricus], and Thirteen-lined ground squirrel [Ictidomys tridecemlineatus]) having been reported to be susceptible to experimental infection with M. leprae. Rats, a food-source in some countries where human leprosy occurs, have been suggested as potential reservoirs for leprosy bacilli, but no evidence supporting this hypothesis is currently available. We screened 301 squirrel samples covering four species (96 Eurasian red squirrels, 67 Eastern grey squirrels (Sciurus carolinensis), 35 Siberian chipmunks, and 103 Pallas’s squirrels (Callosciurus erythraeus)) from Europe and 72 Mexican white-throated woodrats (Neotoma albigula) for the presence of M. leprae and M. lepromatosis using validated PCR protocols. No DNA from leprosy bacilli was detected in any of the samples tested. Given our sample-size, the pathogen should have been detected if the prevalence and/or bacillary load in the populations investigated were similar to those found for British red squirrels. |
| وصف الملف: | application/pdf |
| تدمد: | 2297-1769 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5db8b5555e2cc38bcd59a4b11d9cbbdTest https://pubmed.ncbi.nlm.nih.gov/30775369Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a5db8b5555e2cc38bcd59a4b11d9cbbd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22971769 |
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