Phosphorylation of intrinsically disordered regions in remorin proteins
| العنوان: | Phosphorylation of intrinsically disordered regions in remorin proteins |
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| المؤلفون: | Macarena Marín, Thomas Ott |
| المصدر: | Frontiers in plant science Frontiers in Plant Science, Vol 3 (2012) |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Genetics, Innate immune system, Kinase, phosphorylation, Mini Review, intrinsic disorder, Sequence (biology), Plant Science, Biology, lcsh:Plant culture, Cellular signal transduction, Cell biology, Membrane, Signaling proteins, Phosphorylation, lcsh:SB1-1110, signalling, signaling, MAMP, remorin |
| الوصف: | Plant-specific remorin proteins reside in subdomains of plasma membranes, originally termed membrane rafts. They probably facilitate cellular signal transduction by direct interaction with signalling proteins such as receptor-like kinases (RLKs) and may dynamically modulate their lateral segregation within plasma membranes. Recent evidence suggests such functions of remorins during plant-microbe interactions and innate immune responses, where differential phosphorylation of some of these proteins has been described to be dependent on the perception of the microbe-associated molecular pattern (MAMP) flg22 and the presence of the NBS-LRR resistance protein RPM1. A number of specifically phosphorylated residues in their highly variable and intrinsically disordered N-terminal regions have been identified. Sequence diversity of these evolutionary distinct domains suggests that remorins may serve a wide range of biological functions. Here, we describe patterns and features of intrinsic disorder in remorin protein and discuss possible functional implications of phosphorylation within these rapidly evolving domains. |
| تدمد: | 1664-462X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec100aa71ff5361042910d41a1f54719Test https://pubmed.ncbi.nlm.nih.gov/22639670Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ec100aa71ff5361042910d41a1f54719 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1664462X |
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