دورية أكاديمية

Effects of phenylcapsaicin on aerobic capacity and physiological parameters in active young males: a randomized, triple-blinded, placebo-controlled, crossover trial

التفاصيل البيبلوغرافية
العنوان: Effects of phenylcapsaicin on aerobic capacity and physiological parameters in active young males: a randomized, triple-blinded, placebo-controlled, crossover trial
المؤلفون: Jiménez-Martínez, Pablo, Alix-Fages, Carlos, Janicijevic, Danica, Miras-Moreno, Sergio, Chacón-Ventura, Sara, Martín-Olmedo, Juan J., De La Cruz-Márquez, Juan Carlos, Osuna-Prieto, Francisco J., Jurado-Fasoli, Lucas, Amaro-Gahete, Francisco J., García-Ramos, Amador, Colado, Juan C.
المصدر: Frontiers in Physiology ; volume 14 ; ISSN 1664-042X
بيانات النشر: Frontiers Media SA
سنة النشر: 2023
المجموعة: Frontiers (Publisher - via CrossRef)
مصطلحات موضوعية: Physiology (medical), Physiology
الوصف: Objective: Phenylcapsaicin (PC) is a new capsaicin analog which has exhibited a higher bioavailability. This sudy assessed the effects of a low dose (LD) of 0.625 mg and a high dose (HD) of 2.5 mg of PC on aerobic capacity, substrate oxidation, energy metabolism and exercise physiological variables in young males. Materials and methods: Seventeen active males (age = 24.7 ± 6.0 years) enrolled to this randomized, triple-blinded, placebo-controlled, crossover trial. Participants attended the laboratory on 4 sessions separated by 72–96 h. A submaximal exercise test [to determine maximal fat oxidation (MFO) and the intensity at MFO (FATmax)] followed by a maximal incremental test (to determine VO2 max ) were performed in a preliminary session. The subsequent sessions only differed in the supplement ingested [LD, HD or placebo (PLA)] and consisted of a steady-state test (60 min at FATmax) followed by a maximal incremental test. Energy metabolism, substrate oxidation, heart rate, general (gRPE) and quadriceps (RPEquad) rate of perceived exertion, skin temperature and thermal perception were tested. Results: Clavicle thermal perception was lower in HD compared to PLA and LD ( p = 0.04) across time. HD reduced maximum heart rate in comparison to PLA and LD ( p = 0.03). LD reported higher general RPE (RPEg) values during the steady-state test compared to PLA and HD across time ( p = 0.02). HD and LD elicited higher peak of fat oxidation during the steady-state test compared with PLA ( p = 0.05). Intra-test analyses revealed significant differences for fat oxidation (FATox) in favor of HD and LD compared to PLA ( p = 0.002 and 0.002, respectively), and for carbohydrate oxidation (CHOox) ( p = 0.05) and respiratory exchange ratio (RER) ( p = 0.03) for PLA. In the incremental test, only general RPE at 60% of the maximal intensity (W) differed favoring HD ( p ≤ 0.05). Conclusion: Therefore, PC may contribute to increase aerobic capacity through the improvement of fat oxidation, maximum heart rate and perceptual responses ...
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
DOI: 10.3389/fphys.2023.1190345
DOI: 10.3389/fphys.2023.1190345/full
الإتاحة: https://doi.org/10.3389/fphys.2023.1190345Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.D9F186AE
قاعدة البيانات: BASE