التفاصيل البيبلوغرافية
| العنوان: |
The Role and Function of Mucins and Its Relationship to Inflammatory Bowel Disease |
| المؤلفون: |
Kang, Youra, Park, Hyeonjeong, Choe, Byung-Ho, Kang, Ben |
| المساهمون: |
National Research Foundation |
| المصدر: |
Frontiers in Medicine ; volume 9 ; ISSN 2296-858X |
| بيانات النشر: |
Frontiers Media SA |
| سنة النشر: |
2022 |
| المجموعة: |
Frontiers (Publisher - via CrossRef) |
| الوصف: |
Mucus is present throughout the gastrointestinal tract and is essential for regulating gut microbiota homeostasis and preventing disease by protecting the gastrointestinal barrier from microorganisms, pathogens and toxins or other irritants. Mucin (MUC)-2 is a secreted protein produced by epithelial goblet cells as the main component of mucus. Defects in the gastrointestinal tract, such as inflammation and ulcers, cause damage to the mucus barrier, which can worsen mucus quality and reduce mucus production. Therefore, we would like to review the characteristics of MUC2 and its role in intestinal disorders and highlight the importance of further studies. We also investigated whether the role of MUC2 differs between children and adults, ulcerative colitis (UC) and Crohn's disease (CD). |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| DOI: |
10.3389/fmed.2022.848344 |
| DOI: |
10.3389/fmed.2022.848344/full |
| الإتاحة: |
https://doi.org/10.3389/fmed.2022.848344Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.FAA7B3C0 |
| قاعدة البيانات: |
BASE |
