التفاصيل البيبلوغرافية
| العنوان: |
Gone for 60 seconds: Reactivation length determines motor memory degradation during reconsolidation |
| المؤلفون: |
Nicole Wenderoth, Daniel G. Woolley, Toon T. de Beukelaar |
| المصدر: |
Frontiers in Human Neuroscience. 9 |
| بيانات النشر: |
Frontiers Media SA, 2015. |
| سنة النشر: |
2015 |
| مصطلحات موضوعية: |
Adult, Male, Time Factors, Injury control, Motor sequence, Adolescent, Motor learning, Cognitive Neuroscience, Poison control, Experimental and Cognitive Psychology, Motor Activity, Sequence task, Young Adult, Behavioral Neuroscience, Memory, Humans, Learning, Biological Psychiatry, Chemistry, Reconsolidation, Psychiatry and Mental health, Linear relationship, Neuropsychology and Physiological Psychology, Neurology, Female, Memory consolidation, Psychology, Neuroscience, Motor execution, Psychomotor Performance, Consolidation, Degradation (telecommunications) |
| الوصف: |
When a stable memory is reactivated it becomes transiently labile and requires restabilization, a process known as reconsolidation. Animal studies have convincingly demonstrated that during reconsolidation memories are modifiable and can be erased when reactivation is followed by an interfering intervention. Few studies have been conducted in humans, however, and results are inconsistent regarding the extent to which a memory can be degraded. We used a motor sequence learning paradigm to show that the length of reactivation constitutes a crucial boundary condition determining whether human motor memories can be degraded. In our first experiment, we found that a short reactivation (less than 60 sec) renders the memory labile and susceptible to degradation through interference, while a longer reactivation does not. In our second experiment, we reproduce these results and show a significant linear relationship between the length of memory reactivation and the detrimental effect of the interfering task performed afterwards, i.e., the longer the reactivation, the smaller the memory loss due to interference. Our data suggest that reactivation via motor execution activates a time-dependent process that initially destabilizes the memory, which is then followed by restabilization during further practice. publisher: Elsevier articletitle: Gone for 60 seconds: Reactivation length determines motor memory degradation during reconsolidation journaltitle: Cortex articlelink: http://dx.doi.org/10.1016/j.cortex.2014.07.008Test content_type: article copyright: Copyright © 2014 Elsevier Ltd. All rights reserved. ispartof: Cortex vol:59 pages:138-145 ispartof: location:Italy status: published |
| وصف الملف: |
Print-Electronic; application/pdf |
| تدمد: |
1662-5161 |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4021e22248fdc420aa37abc158098bb5Test
https://doi.org/10.3389/conf.fnhum.2015.217.00311Test |
| حقوق: |
OPEN |
| رقم الانضمام: |
edsair.doi.dedup.....4021e22248fdc420aa37abc158098bb5 |
| قاعدة البيانات: |
OpenAIRE |
