التفاصيل البيبلوغرافية
العنوان: |
Epidemiological pattern of COVID-19 and its association with periodontal health in an urban Indian cohort |
المؤلفون: |
Gupta, Ishita, Patel, Shivani A., Kondal, Dimple, Goodman, Michael, Mohan, Sailesh, Ali, Mohammed K., Tandon, Nikhil, Narayan, K. M. Venkat, Prabhakaran, Dorairaj, Shridhar, Krithiga |
المصدر: |
Front Public Health |
بيانات النشر: |
Frontiers Media S.A. |
سنة النشر: |
2023 |
مصطلحات موضوعية: |
Public Health, demo, envir |
الوصف: |
BACKGROUND: Studies have highlighted a possible influence of gingival and periodontal disease (PD) on COVID-19 risk and severity. However, the evidence is based on hospital-based studies and community-level data are sparse. OBJECTIVES: We described the epidemiological pattern of SARS-CoV-2 infection in Delhi and evaluated the associations of gingival and PD with incident COVID-19 disease in a regionally representative urban Indian population. METHODS: In a prospective study nested within the Centre for Cardiometabolic Risk Reduction in South-Asia (CARRS) study, participants with clinical gingival and periodontal status available at baseline (2014–16) (n = 1,727) were approached between October 2021 to March 2022. Information on COVID-19 incidence, testing, management, severity was collected as per the WHO case criteria along with COVID-19 vaccination status. Absolute incidence of COVID-19 disease was computed by age, sex, and oral health. Differences in rates were tested using log-rank test. Poisson regression models were used to evaluate independent associations between gingival and PD and incidence of COVID-19, adjusted for socio-demographic and behavioral factors, presence of comorbidity, and medication use. RESULTS: Among 1,727 participants, the mean age was 44.0 years, 45.7% were men, 84.5% participants had baseline gingival or PD and 89.4% participants had received at least one dose of COVID-19 vaccine. Overall, 35% (n = 606) participants were tested for COVID-19 and 24% (n = 146/606) tested positive. As per the WHO criteria total number of cases was 210, constituting 12% of the total population. The age and sex-specific rates of COVID-19 were higher among men and older participants, but women aged >60 years had higher rates than men of same age. The incidence rate did not differ significantly between those having gingival or PD and healthy periodontium (19.1 vs. 16.5/1,000 person-years) and there was no difference in risk of COVID-19 by baseline oral disease status. CONCLUSION: Gingival and PD were not ... |
نوع الوثيقة: |
text |
اللغة: |
English |
العلاقة: |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083433Test/ |
الإتاحة: |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083433Test/ |
حقوق: |
undefined |
رقم الانضمام: |
edsbas.30993850 |
قاعدة البيانات: |
BASE |