التفاصيل البيبلوغرافية
| العنوان: |
Molecular mechanisms in successful peripheral regeneration. |
| المؤلفون: |
Makwana, Milan1, Raivich, Gennadij1,2 g.raivich@ucl.ac.uk |
| المصدر: |
FEBS Journal. Jun2005, Vol. 272 Issue 11, p2628-2638. 11p. |
| مصطلحات موضوعية: |
*PERIPHERAL nerve injuries, *CELL adhesion molecules, *CYTOKINES, *CYTOSKELETON, *MITOGENS, *PROTEIN kinases, *NERVOUS system regeneration, *TRANSCRIPTION factors |
| مستخلص: |
Peripheral nerve injury is normally followed by a robust regenerative response. Here we describe the early changes associated with injury from the initial rise in intracellular calcium and the subsequent activation of transcription factors and cytokines leading to an inflammatory reaction, and the expression of growth factors, cytokines, neuropeptides, and other secreted molecules involved in cell-to-cell communication promoting regeneration and neurite outgrowth. The aim of this review is to summarize the molecular mechanisms that play a part in executing successful regeneration. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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