دورية أكاديمية
Autonomic nervous system activation mediates the increase in whole-body glucose uptake in response to electroacupuncture
| العنوان: | Autonomic nervous system activation mediates the increase in whole-body glucose uptake in response to electroacupuncture |
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| المؤلفون: | Benrick, Anna, Kokosar, Milana, Hu, Min, Larsson, Martin, Maliqueo Yevilao, Manuel, Marcondes, Rodrigo Rodrigues, Soligo, Marzia, Protto, Virginia, Jerlhag, Elisabet, Sazonova, Antonina, Behre, Carl Johan, Højlund, Kurt, Thorén, Peter, Stener-Victorin, Elisabet |
| المصدر: | FASEB Journal |
| بيانات النشر: | FASEB |
| سنة النشر: | 2017 |
| المجموعة: | Universidad de Chile: Repositorio académico |
| مصطلحات موضوعية: | Biotechnology, Biochemistry, Molecular Biology, Genetics |
| الوصف: | © FASEB A single bout of low-frequency electroacupuncture (EA) causing muscle contractions increases wholebody glucose uptake in insulin-resistant rats.We explored the underlyingmechanism of this finding andwhether it can be translated into clinical settings. Changes in glucose infusion rate (GIR) were measured by euglycemic– hyperinsulinemic clamp during andafter 45min of low-frequencyEAin 21 overweight/obesewomenwith polycystic ovary syndrome (PCOS) and 21 controls matched for age, weight, and body mass index (experiment 1) and in rats receiving autonomic receptor blockers (experiment 2). GIR was higher after EA in controls and women with PCOS. Plasma serotonin levels and homovanillic acid,markers of vagal activity, decreased in both controls andpatientswith PCOS.Adipose tissue expression of pro-nerve growth factor (proNGF) decreased, and thematureNGF/proNGF ratio increased afterEAin PCOS, but not in controls, suggesting increased sympathetic-driven adipose tissuemetabolism. Administ |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 15306860 08926638 |
| العلاقة: | FASEB Journal, Volumen 31, Issue 8, 2018, Pages 3288-3297; https://repositorio.uchile.cl/handle/2250/167231Test |
| DOI: | 10.1096/fj.201601381R |
| الإتاحة: | https://doi.org/10.1096/fj.201601381RTest https://repositorio.uchile.cl/handle/2250/167231Test |
| حقوق: | Attribution-NonCommercial-NoDerivs 3.0 Chile ; http://creativecommons.org/licenses/by-nc-nd/3.0/clTest/ |
| رقم الانضمام: | edsbas.75B08BC2 |
| قاعدة البيانات: | BASE |
| تدمد: | 15306860 08926638 |
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| DOI: | 10.1096/fj.201601381R |