دورية أكاديمية
A path to translation: How 3D patient tumor avatars enable next generation precision oncology.
| العنوان: | A path to translation: How 3D patient tumor avatars enable next generation precision oncology. |
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| المؤلفون: | Bose, Shree, Barroso, Margarida, Chheda, Milan G, Clevers, Hans, Elez, Elena, Kaochar, Salma, Kopetz, Scott E, Li, Xiao-Nan, Meric-Bernstam, Funda, Meyer, Clifford A, Mou, Haiwei, Naegle, Kristen M, Pera, Martin, Perova, Zinaida, Politi, Katerina A, Raphael, Benjamin J, Robson, Paul, Sears, Rosalie C, Tabernero, Josep, Tuveson, David A, Welm, Alana L, Welm, Bryan E, Willey, Christopher D, Salnikow, Konstantin, Chuang, Jeffrey H, Shen, Xiling |
| المصدر: | Faculty Research 2022 |
| بيانات النشر: | The Mouseion at the JAXlibrary |
| سنة النشر: | 2022 |
| المجموعة: | The Jackson Laboratory: The Mouseion at the JAXlibrary |
| مصطلحات موضوعية: | JMG, JGM, Humans, Neoplasms, Precision Medicine, Prospective Studies, Medical Oncology, Life Sciences, Medicine and Health Sciences |
| الوصف: | 3D patient tumor avatars (3D-PTAs) hold promise for next-generation precision medicine. Here, we describe the benefits and challenges of 3D-PTA technologies and necessary future steps to realize their potential for clinical decision making. 3D-PTAs require standardization criteria and prospective trials to establish clinical benefits. Innovative trial designs that combine omics and 3D-PTA readouts may lead to more accurate clinical predictors, and an integrated platform that combines diagnostic and therapeutic development will accelerate new treatments for patients with refractory disease. |
| نوع الوثيقة: | text |
| اللغة: | unknown |
| العلاقة: | https://mouseion.jax.org/stfb2022/258Test; https://doi.org/10.1016/j.ccell.2022.09.017Test |
| DOI: | 10.1016/j.ccell.2022.09.017 |
| الإتاحة: | https://doi.org/10.1016/j.ccell.2022.09.017Test https://mouseion.jax.org/stfb2022/258Test |
| رقم الانضمام: | edsbas.23A897E5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.ccell.2022.09.017 |
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