Proteomics approaches in cervical cancer: focus on the discovery of biomarkers for diagnosis and drug treatment monitoring
| العنوان: | Proteomics approaches in cervical cancer: focus on the discovery of biomarkers for diagnosis and drug treatment monitoring |
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| المؤلفون: | Antonia Vlahou, Kalliopi I. Pappa, Georgia Kontostathi, Nicholas P. Anagnou, Manousos Makridakis, Jerome Zoidakis |
| المصدر: | Expert Review of Proteomics. 13:731-745 |
| بيانات النشر: | Informa UK Limited, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Proteomics, 0301 basic medicine, Uterine Cervical Neoplasms, Bioinformatics, Biochemistry, 03 medical and health sciences, Drug treatment, 0302 clinical medicine, Biomarkers, Tumor, Humans, Medicine, Pap test, Papillomaviridae, Molecular Biology, Early Detection of Cancer, Cervical cancer, biology, medicine.diagnostic_test, business.industry, Papillomavirus Infections, biology.organism_classification, medicine.disease, female genital diseases and pregnancy complications, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, business, Cervical cancer incidence |
| الوصف: | The HPV virus accounts for the majority of cervical cancer cases. Although a diagnostic tool (Pap Test) is widely available, cervical cancer incidence still remains high worldwide, and especially in developing countries, attributed to a large extent to suboptimal sensitivities of the Pap test and unavailability of the test in developing countries.Proteomics approaches have been used in order to understand the HPV virus correlation to cervical cancer pathology, as well as to discover putative biomarkers for early cervical cancer diagnosis and drug mode of action. Expert commentary: The present review summarizes the latest in vitro and in vivo proteomic studies for the discovery of putative cervical cancer biomarkers and the evaluation of available drugs and treatments. |
| تدمد: | 1744-8387 1478-9450 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ec0824c84c646b04deac44f00f8a60Test https://doi.org/10.1080/14789450.2016.1210514Test |
| رقم الانضمام: | edsair.doi.dedup.....24ec0824c84c646b04deac44f00f8a60 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17448387 14789450 |
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