Hematopoietic stem cell transplantation in older persons: respecting the heterogeneity of age

التفاصيل البيبلوغرافية
العنوان: Hematopoietic stem cell transplantation in older persons: respecting the heterogeneity of age
المؤلفون: Laura C. Michaelis, Parameswaran Hari, Mehdi Hamadani
المصدر: Expert review of hematology. 7(3)
سنة النشر: 2014
مصطلحات موضوعية: Gerontology, Aged, 80 and over, Male, Population ageing, education.field_of_study, Transplantation Conditioning, Hematopoietic cell, business.industry, medicine.medical_treatment, Incidence, Population, Age Factors, Hematopoietic Stem Cell Transplantation, Hematology, Hematopoietic stem cell transplantation, Additional research, Transplantation, Hematological malignancy, Medicine, Humans, Female, Stem cell, education, business, Aged
الوصف: Demographic trends establish that older adults are the fastest growing segment of population, with over 19% of the population expected to be aged >65 years by 2030. As the risk for hematologic malignancies increases with age, it is imperative that our field continues to strive to individualize and manage risk and benefit in an aging population. While hematologic diseases are more common in the elderly, only a small minority of patients with hematological malignancy aged >65 years receive allogeneic hematopoietic cell transplantation, relative to the burden of disease in this population. In this editorial we explore some of the obstacles to transplantation, the rationale to consider the procedure in the older adult and ways that the stem cell consultative process can be individualized. Finally, we outline key areas where additional research is needed.
تدمد: 1747-4094
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9e8eaf7faa91c4e5533e5f5c208f7bTest
https://pubmed.ncbi.nlm.nih.gov/24785114Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....cb9e8eaf7faa91c4e5533e5f5c208f7b
قاعدة البيانات: OpenAIRE