Improving adherence in osteoporosis: a new management algorithm for the patient with osteoporosis
| العنوان: | Improving adherence in osteoporosis: a new management algorithm for the patient with osteoporosis |
|---|---|
| المؤلفون: | Giovanni Iolascon, Mario Barbagallo, Gianluca Baio, G. D'Avola, Andrea Di Luccio, Nazzarena Malavolta, Fabio Massimo Ulivieri, Gian Luca Di Tanna, Federico Robbiati, Paolo Falaschi |
| المساهمون: | Baio, Gianluca, Barbagallo, Mario, D'Avola, Giovanni, Di Luccio, Andrea, Di Tanna, Gian Luca, Falaschi, Paolo, Iolascon, Giovanni, Malavolta, Nazzarena, Robbiati, Federico, Ulivieri, Fabio Massimo, Baio, G, Barbagallo, M, D’Avola, G, Di Luccio, A, Di Tanna, G, Falaschi, P, Iolascon, G, Malavolta, N, Robbiati, R, Ulivieri, F, D'Avola, G, Di Tanna, Gl, Robbiati, F, Ulivieri, Fm |
| المصدر: | Expert Opinion on Pharmacotherapy. 12:257-268 |
| بيانات النشر: | Informa Healthcare, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | medicine.medical_specialty, Bone Density Conservation Agent, Bone density, Osteoporosis, Alternative medicine, adherence, osteoporosis, treatment algorithm, bone density, medication possession ratio, bisphosphonates, Medication Adherence, Clinical Protocols, Cost of Illness, Treatment algorithm, medicine, Humans, Bisphosphonate, Pharmacology (medical), Dosing, Clinical Protocol, Adverse effect, MED/01 - STATISTICA MEDICA, Osteoporosis, Postmenopausal, Adherence, bisphosphonates, bone density, medication possession ratio, osteoporosis, treatment algorithm, Medication possession ratio, Pharmacology, Bone Density Conservation Agents, business.industry, Osteoporosi, General Medicine, medicine.disease, Algorithm, Cost of Illne, Clinical trial, Treatment Outcome, Zoledronic acid, Adherence, Bisphosphonates, Algorithms, Female, Physical therapy, business, Human, medicine.drug |
| الوصف: | Introduction: Bisphosphonates are the first-choice treatment for osteoporosis. They effectively increase bone mineral density, reduce markers of bone resorption, and lower the incidence of new fractures in patients with osteoporosis-related fracture. However, the efficacy observed in clinical trials may not be realized in a real-life setting, partly due to poor adherence to therapy, with a significant worsening of clinical outcomes. Several issues contribute to poor adherence to osteoporosis medication, including inconvenient dosing regimens and concerns about possible adverse events. Although strategies to improve adherence have been investigated, new approaches are required. Areas covered: We review available data and propose a new approach to improve adherence to osteoporosis therapy in clinical practice. We present the current evidence and personal experience from a group of Italian osteoporosis experts. Expert opinion: To improve adherence, we propose a multifaceted approach, which includes the Triad Model suggested by the World Health Organization, direct observed therapy and the use of drugs with longer administration intervals, e.g., zoledronic acid. The integration of these strategies may provide the basis for a marked increase in adherence to osteoporosis therapy, and improved clinical outcomes in a real-life scenario. © 2011 Informa UK, Ltd. |
| تدمد: | 1744-7666 1465-6566 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfbdc406fbdbbebe9af57c0d0a97d61Test https://doi.org/10.1517/14656566.2011.537259Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....abfbdc406fbdbbebe9af57c0d0a97d61 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17447666 14656566 |
|---|