Regulation of the retinal interphotoreceptor matrix Na by the retinal pigment epithelium during the light response
| العنوان: | Regulation of the retinal interphotoreceptor matrix Na by the retinal pigment epithelium during the light response |
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| المؤلفون: | I. Armstrong, C. Wigham, S. Hodson |
| المصدر: | Experientia. 50:438-441 |
| بيانات النشر: | Springer Science and Business Media LLC, 1994. |
| سنة النشر: | 1994 |
| مصطلحات موضوعية: | Cell Membrane Permeability, Light, genetic structures, Sodium, chemistry.chemical_element, In Vitro Techniques, Interphotoreceptor matrix, Biology, Blood–brain barrier, Sodium Channels, Membrane Potentials, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Chlorides, medicine, Animals, Photoreceptor Cells, Pigment Epithelium of Eye, Molecular Biology, Ion transporter, Pharmacology, Membrane potential, Retina, Retinal pigment epithelium, Choroid, Retinal, Cell Biology, Anatomy, Darkness, eye diseases, Bicarbonates, medicine.anatomical_structure, chemistry, Potentiometry, Biophysics, Molecular Medicine, Rabbits, sense organs, Sclera |
| الوصف: | We examined the rabbit retinal pigment epithelium (RPE) for Na transport properties which would allow it to buffer undesirable changes in Na concentrations in the interphotoreceptor matrix (IPM) during light and dark cycles. The RPE is selectivity permeable to sodium. Open and short circuit transport studies with RPE indicate a circulating (choroid to retina and back) Na current which does not compromise the electrical integrity of the blood brain barrier but together with the Na permeselectivity is of sufficient magnitude to buffer both upwards and downwards movements of IPM [Na] during light or dark responses. |
| تدمد: | 1420-9071 0014-4754 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4441593291e40ed2f04cfcc2210a74Test https://doi.org/10.1007/bf01920742Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....de4441593291e40ed2f04cfcc2210a74 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14209071 00144754 |
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