المؤلفون: Iris F. Rey, Ch. G. Crispens

المصدر: Experientia. 23:681-683

مصطلحات موضوعية: Pharmacology, L-Lactate Dehydrogenase, Cell Biology, Biology, Thymectomy, biology.organism_classification, Virology, Virus, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Rickettsia, Animals, Newborn, chemistry, Virus Diseases, Lactate dehydrogenase, Animals, Viruses, Unclassified, Molecular Medicine, Molecular Biology, Neonatal thymectomy

الوصف: Die gegebenen Befunde lassen vermuten, dass neonatale Thymektomie und/oder Infektion mit LDH-Virus einen Effekt auf eine Anzahl von Faktoren wie LDH-Plasma-Spiegel, Gewichtserhohung und Lebensdauer in Mausen hervorrufen konnen. Der Virustiter im Plasma ist vom Zeitpunkt der Infektion abhangig.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c2775128f7a19535981a78c089703aTest
https://doi.org/10.1007/bf02144202Test

المؤلفون: Theresa C. Bienieki, Walter C. Quevedo, Thomas J. Holstein, H. J. Dyer

المصدر: Experientia. 31(9)

مصطلحات موضوعية: C57BL/6, Male, Tail, Mice, Nude, Mice, Inbred Strains, Hindlimb, Biology, Isozyme, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Lactate dehydrogenase, Animals, Molecular Biology, Polyacrylamide gel electrophoresis, Skin, Pharmacology, Back, integumentary system, Epidermis (botany), L-Lactate Dehydrogenase, Pinna, Ear, Cell Biology, Anatomy, biology.organism_classification, Trunk, Isoenzymes, Mice, Inbred C57BL, chemistry, Molecular Medicine, Female, sense organs

الوصف: Five isozymes of LDH are demonstrable in the epidermis of the ear pinnae, hind feet, trunk dorsa, and tails of adult C57BL, C57HR, and C3HB mice by polyacrylamide gel electrophoresis. LDH-5 activity predominates in electropherograms. The ratio of LDH-1 to LDH-K is greater in the epidermis of ear pinna and trunk dorsum than in that of tail and hind foot. The region-specific patterns of epidermal LDH isozymes are not correlated with melanin pigmentation or "hairiness' of the skin.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1636e55e56c96259be1d606061cd55e4Test
https://pubmed.ncbi.nlm.nih.gov/1175739Test

المؤلفون: K. E. K. Rowson

المصدر: Experientia. 36(9)

مصطلحات موضوعية: Pharmacology, L-Lactate Dehydrogenase, Host (biology), viruses, Lactate dehydrogenase-elevating virus, food and beverages, virus diseases, Cell Biology, Lactic dehydrogenase, Biology, Virology, Virus, Cellular and Molecular Neuroscience, Chronic infection, chemistry.chemical_compound, Mice, chemistry, Lactate dehydrogenase, Molecular Medicine, Animals, Molecular Biology

الوصف: Lactic dehydrogenase virus has been found to replicate and maintain a chronic infection in the Asian mouse Mus caroli as it does in Mus musculus. However, the level of viraemia is lower and the increase in plasma lactate dehydrogenase activity very much less.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23398bf0162ee6d695c99373c25cf59Test
https://pubmed.ncbi.nlm.nih.gov/7418841Test

المؤلفون: Shiva M. Singh, Ann Phillips, Caroline H. Wang

المصدر: Experientia. 38(12)

مصطلحات موضوعية: medicine.medical_specialty, Aging, Pyruvate dehydrogenase kinase, Genotype, Pyruvate Kinase, Biology, Kidney, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Lactate dehydrogenase, Internal medicine, medicine, Animals, Muscular dystrophy, Molecular Biology, Pharmacology, chemistry.chemical_classification, L-Lactate Dehydrogenase, Cell Biology, Metabolism, Muscular Dystrophy, Animal, medicine.disease, Molecular biology, Mice, Mutant Strains, Isoenzymes, medicine.anatomical_structure, Enzyme, Endocrinology, chemistry, Organ Specificity, Mutation, Molecular Medicine, Pyruvate kinase

الوصف: The genotype difference (dystrophic vs nondystrophic) in the LDH isozymes is observed in kidney. These differences are evident only at birth and at early developmental stages (before the expression of dystrophic symptoms). The tissue specific genotype differences for PK are limited to the thigh muscle (M form) and heart (L form), after the onset of the condition. These differences may reflect the pleiotropic effect of the dy2J locus during the temporal regulation of these and other enzymes implicated in muscular dystrophy (MD).

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c9f7d45a27e7d1a2565daaae570e86Test
https://pubmed.ncbi.nlm.nih.gov/7151975Test

المؤلفون: Ch. G. Crispens, D. M. Stark

المصدر: Experientia. 21(5)

مصطلحات موضوعية: Pharmacology, animal structures, L-Lactate Dehydrogenase, Chemistry, L-Lactate dehydrogenase, Cell Biology, Lactic dehydrogenase, Virus diseases, Clinical Enzyme Tests, In Vitro Techniques, Molecular biology, Cellular and Molecular Neuroscience, Mice, Blood, Virus Diseases, Molecular Medicine, Animals, Molecular Biology

الوصف: Observations sur la multiplication de deux particules differentes de virus dans le serum de la sour's apres infection par l'agent de LDH. Le fait que la grande particule a disparu du serum sept semaines apres l'infection suggere que la petite particule est responsable de la viremie persistante et du taux eleve de l'enzyme dans le sang des animaux infectes.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a48e82e8f9bf206262c4df84ebe9b5bTest
https://pubmed.ncbi.nlm.nih.gov/5841258Test

المؤلفون: W. K. Whitten, Ch. G. Crispens

المصدر: Experientia. 27(1)

مصطلحات موضوعية: Male, Virus, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Species Specificity, Lactate dehydrogenase, Animals, RNA Viruses, Sex Ratio, Molecular Biology, Pharmacology, biology, L-Lactate Dehydrogenase, Cell Biology, Strain difference, biology.organism_classification, Virology, Spermatozoa, Rickettsia, chemistry, Animals, Newborn, Virus Diseases, Molecular Medicine, Female, Sex ratio

الوصف: Durch Infektion mit LDH-Virus wird bei Mausen, deren Nachkommen normalerweise ein Geschlechtsverhaltnis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c4f631428a1a953f65439dd471e2fcTest
https://pubmed.ncbi.nlm.nih.gov/5549235Test

المؤلفون: J. Britton-Davidian, A. Ruiz Bustos, M. Topal, L. Thaler

المصدر: Experientia. 34:1144-1145

مصطلحات موضوعية: Pharmacology, Genetics, education.field_of_study, Polymorphism, Genetic, L-Lactate Dehydrogenase, Population, Locus (genetics), Cell Biology, Environment, Biology, Isoenzymes, Sexual dimorphism, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Species Specificity, chemistry, Lactate dehydrogenase, Animals, Hybridization, Genetic, Molecular Medicine, Allele, education, Molecular Biology, Gene

الوصف: First variation at the Ldh-A locus and a new allele at the Ldh-B locus are reported in a M. musculus population dimorphic at the Ldh-A locus and in a M. spretus population trimorphic at the Ldh-B locus.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09ae388c09cb301b7e33ec69dba1121Test
https://doi.org/10.1007/bf01922920Test

المؤلفون: G. T. Gustafson, U. Lerner

المصدر: Experientia. 35:525-526

مصطلحات موضوعية: medicine.medical_specialty, Enzyme release, chemistry.chemical_element, L-Lactate dehydrogenase, Calcium, Bone and Bones, Bone resorption, Phosphates, Mice, Cellular and Molecular Neuroscience, Inorganic phosphate, Culture Techniques, Internal medicine, medicine, Animals, Bone Resorption, Molecular Biology, Pharmacology, chemistry.chemical_classification, L-Lactate Dehydrogenase, biology, Alanine Transaminase, Cell Biology, Levamisole, Glucose, Endocrinology, Enzyme, Biochemistry, chemistry, Alanine transaminase, Lactates, biology.protein, Molecular Medicine, Lysosomes, medicine.drug

الوصف: Levamisole added to cultured calvarial bones inhibited spontaneous bone resorption, as indicated by reduced release of calcium and inorganic phosphate to the medium. In addition, levamisole reduced lactate production and release of lysosomal enzymes.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b960378820fdecc512fc46e196082d84Test
https://doi.org/10.1007/bf01922748Test

المؤلفون: H. G. Eibs, H. Spielmann, C. Mentzel

المصدر: Experientia. 32:1085-1086

مصطلحات موضوعية: Male, medicine.medical_specialty, Biology, Chromatography, Affinity, Sepharose, Matrix (chemical analysis), Mice, Cellular and Molecular Neuroscience, Affinity chromatography, Internal medicine, Testis, medicine, Animals, Molecular Biology, Pharmacology, chemistry.chemical_classification, Chromatography, L-Lactate Dehydrogenase, Ldh isozymes, Elution, Cell Biology, NAD, In vitro, Isoenzymes, Endocrinology, Enzyme, chemistry, Molecular Medicine, Lactate dehydrogenase-X

الوصف: At concentrations of 200 muM NADH and 0.5 M NaCl LDH-X is separated from the other LDH isozymes of mouse testes on oxamate-sepharose. In a second step LDH-X is bound to the same matrix at lower NADH and NaCl concentrations and the pure enzyme can subsequently be eluted.Results of a method of rapid purification of lactate dehydrogenase X (LDH-X) from mouse testes by 2 stepts of affinity chromatography on oxamate-sepharose at different sodium chloride (NaCl) and NADH concentrations are discussed. At concentrations of 200 mcM NADH and .5 M NaCl, LDH-X is separated from other LDH isoenzymes. The binding of LDH-X to the column is then carried out on the unbound fractions containing LDH-X and contaminating proteins after a 1:5 dilution. The resulting NADH and NaCl concentrations allow the binding of LDH-X. The specific activity of purified mouse LDH-X from testes was 120 IU/mg. The main advantage of this technique is the rapidity and ease of purification.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd0900df58f3cbc0d719c36091b2c8bTest
https://doi.org/10.1007/bf01933984Test

المؤلفون: C. G. Crispens

المصدر: Experientia. 25:1197-1198

مصطلحات موضوعية: Pharmacology, L-Lactate Dehydrogenase, Cell Biology, Biology, Molecular biology, Virus, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Biochemistry, chemistry, Lactate dehydrogenase, Animals, RNA Viruses, Molecular Medicine, Sex Ratio, Molecular Biology

الوصف: On met en evidence le fait que le virus LDH exerce un effet sur la proportion des sexes chez les souris par l'intermediaire du pere. En ce qui concerne le mecanisme implique dans ce phenomene, les resultats obtenus jusqu'a present semblent insuffisants pour permettre une conclusion.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3020a4c5ac7e6d71de053fcdd7bd60d5Test
https://doi.org/10.1007/bf01900274Test