التفاصيل البيبلوغرافية
| العنوان: |
高渗盐水治疗颅内高压的最新研究进展. (Chinese) |
| العنوان البديل: |
Latest Progress of Hypertonic Saline in the Treatment of Intracranial Hypertension. (English) |
| المؤلفون: |
郑佳男, 程迎新, 曹培成, 李爱军 |
| المصدر: |
Evaluation & Analysis of Drug-Use in Hospitals of China; 2022, Vol. 22 Issue 12, p1533-1536, 4p |
| مصطلحات موضوعية: |
HYPERTONIC saline solutions, DRYING agents, HEMORHEOLOGY, INTRACRANIAL hypertension, CARDIOVASCULAR system |
| الملخص (بالإنجليزية): |
Intracranial hypertension is mainly caused by brain edema induced by different diseases, the key points of the treatment of brain edema is to pump water from the brain tissue into the intravascular space to reduce intracranial pressure by dehydrating agents, that is osmotic pressure therapy, and the most common used dehydrating agents are mannitol and hypertonic saline. Researches suggest that hypertonic saline may have more profound and long-lasting effect in reducing intracranial hypertension compared with mannitol. Therefore, the hypertonic saline has been widely used in the treatment of clinical cerebral edema in recent years, mainly by its mechanism of altering osmolarity, improving blood rheology, circulatory system and immune regulatory. However, there are inconsistencies in the dose, frequency, concentration and administration route of hypertonic saline. This paper reviews the treatment of intracranial hypertension with hypertonic saline. [ABSTRACT FROM AUTHOR] |
| Abstract (Chinese): |
颅内高压主要是由不同疾病引起的脑水肿所致, 脑水肿的治疗重点是利用脱水剂从脑组织中抽出水进入血管内空间来 降低颅内压, 即渗透压疗法, 临床上最常见的脱水剂为甘露醇和高渗盐水。研究结果表明, 与甘露醇相比, 高渗盐水在降低颅内高 压方面可能具有更深远和持久的作用。因此, 近年来高渗盐水被广泛应用于临床脑水肿的治疗, 主要利用其改变渗透压, 改善血 液流变学、循环系统以及免疫调节机制。但对于高渗盐水使用剂量、频率、浓度和给药途径等方面存在不一致之处。故本研究对 高渗盐水治疗颅内高压进行综述。 [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
