The dynamic changes of dominant clones of Staphylococcus aureus causing bloodstream infections in the European region: Results of a second structured survey
| العنوان: | The dynamic changes of dominant clones of Staphylococcus aureus causing bloodstream infections in the European region: Results of a second structured survey |
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| المؤلفون: | Grundmann, H, Schouls, L M, Aanensen, D M, Pluister, G N, Tami, A, Chlebowicz, M, Glasner, C, Sabat, A J, Weist, K, Heuer, O, Friedrich, A W, ESCMID Study Group on Molecular Epidemiological Markers, European Staphylococcal Reference Laboratory Working Group, Perez-Vazquez, Maria |
| المساهمون: | Unión Europea. European Centre for Disease Prevention and Control (ECDC), ESCMID Study Group on Molecular Epidemiological Markers, European Staphylococcal Reference Laboratory Working Group, Denis, O., Nashev, D., Blanc, D.S., Pieridou-Bagatzouni, D., Jakubu, V., Zemlickova, H., Westh, H., Larsen, A.R., Skov, R., Laurent, F., Layer, F., Witte, W., Spiliopoulou, I., Salmenlinna, S., Lindholm, L., Vuopio-Varkila, J., Toth, A., Ungvari, E., Brennan, G., Shore, A., Miklasevics, E., Balode, A., Haraldsson, G., Kristinsson, K.G., Monaco, M., Pantosti, A., Borg, M., Huijsdens, X., Heck, M., Marstein, L., Jacobsen, T., Gran, F., Faria, N., de Lencastre, H., Empel, J., Kozińska, A., Hryniewicz, W., Codita, I., Perez-Vazquez, M., Vindel, A., Švent Kučina, N., Haeggman, S., Liljequist, B.O., Pichon, B., Kearns, A., Edwards, G., Microbes in Health and Disease (MHD) |
| المصدر: | Europe PubMed Central Euro surveillance, vol. 19, no. 49 Eurosurveillance, 19(49), 35-44. EUR CENTRE DIS PREVENTION & CONTROL |
| بيانات النشر: | European Centre for Disease Control and Prevention (ECDC), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, Methicillin-Resistant Staphylococcus aureus, Staphylococcus aureus, medicine.medical_specialty, Genotype, Epidemiology, Human pathogen, Microbial Sensitivity Tests, medicine.disease_cause, Microbiology, EMERGENCE, Virology, medicine, Humans, Typing, Staphylococcal Protein A, Anti-Bacterial Agents/pharmacology, Bacterial Typing Techniques, Data Collection, Europe, Female, Genetic Variation, Molecular Epidemiology, Multilocus Sequence Typing, Staphylococcal Infections/blood, Staphylococcal Infections/epidemiology, Staphylococcal Infections/microbiology, Staphylococcal Protein A/genetics, Staphylococcus aureus/classification, Staphylococcus aureus/drug effects, Staphylococcus aureus/genetics, Staphylococcus aureus/isolation & purification, Molecular epidemiology, business.industry, Public Health, Environmental and Occupational Health, Staphylococcal Infections, Methicillin-resistant Staphylococcus aureus, Anti-Bacterial Agents, Multilocus sequence typing, SPREAD, business |
| الوصف: | Staphylococcus aureus is one of the most important human pathogens and meticillin-resistant S. aureus (MRSA) presents a major cause of healthcare- and community-acquired infections. This study investigated the spatial and temporal changes of S. aureus causing bacteraemia in Europe over a five-year interval and explored the possibility of integrating pathogen-based typing data with epidemiological and clinical information at a European level. Between January 2011 and July 2011, 350 laboratories serving 453 hospitals in 25 countries collected 3,753 isolates (meticillin-sensitive S. aureus (MSSA) and MRSA) from patients with S. aureus bloodstream infections. All isolates were sent to the national staphylococcal reference laboratories and characterised by quality-controlled spa typing. Data were uploaded to an interactive web-based mapping tool. A wide geographical distribution of spa types was found, with some prevalent in all European countries. MSSA was more diverse than MRSA. MRSA differed considerably between countries with major international clones expanding or receding when compared to a 2006 survey. We provide evidence that a network approach of decentralised typing and visualisation of aggregated data using an interactive mapping tool can provide important information on the dynamics of S. aureus populations such as early signalling of emerging strains, cross-border spread and importation by travel. The study was funded by ECDC through tender and frame-work contract ECDC 09/033. Sí |
| وصف الملف: | application/pdf |
| تدمد: | 1560-7917 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3079c8f3f417503138515f9d726765Test https://doi.org/10.2807/1560-7917.es2014.19.49.20987Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5d3079c8f3f417503138515f9d726765 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15607917 |
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