Assessing the Clinical Utility of Published Prostate Cancer Polygenic Risk Scores in a Large Biobank Data Set

التفاصيل البيبلوغرافية
العنوان: Assessing the Clinical Utility of Published Prostate Cancer Polygenic Risk Scores in a Large Biobank Data Set
المؤلفون: Vince, Randy A., Sun, Helen, Singhal, Udit, Schumacher, Fredrick R., Trapl, Erika, Rose, Johnie, Cullen, Jennifer, Zaorsky, Nicholas, Shoag, Jonathan, Hartman, Holly, Jia, Angela Y., Spratt, Daniel E., Fritsche, Lars G., Morgan, Todd M.
المصدر: European Urology Oncology; 20240101, Issue: Preprints
مستخلص: Polygenic risk scores have modest ability to identify men at higher risk of prostate cancer but lack the clinical utility to determine which men are at the highest risk of clinically significant prostate cancer.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:25889311
DOI:10.1016/j.euo.2024.04.017