Grading of Crohn’s disease activity using CT, MRI, US and scintigraphy: a meta-analysis
| العنوان: | Grading of Crohn’s disease activity using CT, MRI, US and scintigraphy: a meta-analysis |
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| المؤلفون: | Jaap Stoker, Carl A. J. Puylaert, Shandra Bipat, Jeroen A. W. Tielbeek |
| المساهمون: | AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Radiology and Nuclear Medicine, ACS - Amsterdam Cardiovascular Sciences, CCA -Cancer Center Amsterdam |
| المصدر: | European Radiology European radiology, 25(11), 3295-3313. Springer Verlag |
| بيانات النشر: | Springer Berlin Heidelberg, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Crohn’s disease, Adult, Male, medicine.medical_specialty, Gastrointestinal, Adolescent, Radionuclide imaging, Scintigraphy, Sensitivity and Specificity, 030218 nuclear medicine & medical imaging, Irritable Bowel Syndrome, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Crohn Disease, Biopsy, Ultrasound, medicine, Humans, Radiology, Nuclear Medicine and imaging, Grading (tumors), Neuroradiology, Aged, Ultrasonography, X-ray computed tomography, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, Interventional radiology, General Medicine, Middle Aged, Reference Standards, Magnetic Resonance Imaging, 3. Good health, Radiology Nuclear Medicine and imaging, Meta-analysis, Positron-Emission Tomography, 030211 gastroenterology & hepatology, Female, Tomography, Radiology, Nuclear medicine, business, Tomography, X-Ray Computed |
| الوصف: | Purpose To assess the grading of Crohn’s disease activity using CT, MRI, US and scintigraphy. Materials and methods MEDLINE, EMBASE and Cochrane databases were searched (January 1983–March 2014) for studies evaluating CT, MRI, US and scintigraphy in grading Crohn’s disease activity compared to endoscopy, biopsies or intraoperative findings. Two independent reviewers assessed the data. Three-by-three tables (none, mild, frank disease) were constructed for all studies, and estimates of accurate, over- and under-grading were calculated/summarized by fixed or random effects models. Results Our search yielded 9356 articles, 19 of which were included. Per-patient data showed accurate grading values for CT, MRI, US and scintigraphy of 86 % (95 % CI: 75–93 %), 84 % (95 % CI: 67–93 %), 44 % (95 % CI: 28–61 %) and 40 % (95 % CI: 16–70 %), respectively. In the per-patient analysis, CT and MRI showed similar accurate grading estimates (P = 0.8). Per-segment data showed accurate grading values for CT and scintigraphy of 87 % (95 % CI: 77–93 %) and 86 % (95 % CI: 80–91 %), respectively. MRI and US showed grading accuracies of 67–82 % and 56–75 %, respectively. Conclusions CT and MRI showed comparable high accurate grading estimates in the per-patient analysis. Results for US and scintigraphy were inconsistent, and limited data were available. Key Points • CT and MRI have comparable high accuracy in grading Crohn’s disease. • Data on US and scintigraphy is inconsistent and limited. • MRI is preferable over CT as it lacks ionizing radiation exposure. Electronic supplementary material The online version of this article (doi:10.1007/s00330-015-3737-9) contains supplementary material, which is available to authorized users. |
| اللغة: | English |
| تدمد: | 1432-1084 0938-7994 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b1dcce0702c37305e5c86c27e80e19Test http://europepmc.org/articles/PMC4595539Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....41b1dcce0702c37305e5c86c27e80e19 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14321084 09387994 |
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