Aerobic interval training reduces blood pressure and improves myocardial function in hypertensive patients
| العنوان: | Aerobic interval training reduces blood pressure and improves myocardial function in hypertensive patients |
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| المؤلفون: | Asbjørn Støylen, Inger-Lise Aamot, Inga Schjerve Ekeberg, Ulrik Wisløff, Charlotte Bjork Ingul, Arnt Erik Tjønna, Harald Edvard Mølmen-Hansen, Gjertrud Aunet Tyldum, Tomas Stølen |
| المصدر: | European Journal of Preventive Cardiology. 19:151-160 |
| بيانات النشر: | Oxford University Press (OUP), 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Epidemiology, Diastole, Blood Pressure, Interval training, Oxygen Consumption, Tissue Doppler echocardiography, Heart Rate, Internal medicine, Heart rate, Humans, Medicine, Exercise physiology, Systole, Exercise, business.industry, Middle Aged, Myocardial Contraction, Echocardiography, Doppler, Exercise Therapy, Blood pressure, medicine.anatomical_structure, Cardiovascular Diseases, Echocardiography, Hypertension, Quality of Life, Vascular resistance, Cardiology, Female, Vascular Resistance, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Exercise is recommended as prevention, management, and control of all stages of hypertension. There are still controversies about the optimal training dose, frequency, and intensity. We aimed to study the effect of aerobic interval training on blood pressure and myocardial function in hypertensive patients.A total of 88 patients (52.0 ± 7.8 years, 39 women) with essential hypertension were randomized to aerobic interval training (AIT) (90% of maximal heart rate, correlates to 85-90% of VO(2max)), isocaloric moderate intensity continuous training (MIT) (~70% of maximal heart rate, 60% of VO(2max)), or a control group. Exercise was performed on a treadmill, three times per week for 12 weeks. Ambulatory 24-hour blood pressure (ABP) was the primary endpoint. Secondary endpoints included maximal oxygen uptake (VO(2max)), mean heart rate/24 hour, flow mediated dilatation (FMD), total peripheral resistance (TPR), and myocardial systolic and diastolic function by echocardiography. Systolic ABP was reduced by 12 mmHg (p 0.001) in AIT and 4.5 mmHg (p = 0.05) in MIT. Diastolic ABP was reduced by 8 mmHg (p 0.001) in AIT and 3.5 mmHg (p = 0.02) in MIT. VO(2max) improved by 15% (p 0.001) in AIT and 5% (p 0.01) in MIT. Systolic myocardial function improved in both exercise groups, diastolic function in the AIT group only. TPR reduction and increased FMD were only observed in the AIT group.This study indicates that the blood pressure reducing effect of exercise in essential hypertension is intensity dependent. Aerobic interval training is an effective method to lower blood pressure and improve other cardiovascular risk factors. |
| تدمد: | 2047-4881 2047-4873 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7197b0cfa8cbbc2600bb5c7e693b90Test https://doi.org/10.1177/1741826711400512Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....ef7197b0cfa8cbbc2600bb5c7e693b90 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20474881 20474873 |
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