An Important Risk Factor Affecting Hypercalciuria in Children: Vesicoureteral Reflux

التفاصيل البيبلوغرافية
العنوان: An Important Risk Factor Affecting Hypercalciuria in Children: Vesicoureteral Reflux
المؤلفون: Oguzhan Kahraman, Meylis Artykov, Serdar Tekgul, Hakan Bahadir Haberal, Berk Hazir, Mesut Altan, Burak Citamak, Hasan Serkan Dogan
المصدر: European Journal of Pediatric Surgery. 31:530-534
بيانات النشر: Georg Thieme Verlag KG, 2020.
سنة النشر: 2020
مصطلحات موضوعية: medicine.medical_specialty, Creatinine, business.industry, 030232 urology & nephrology, Urology, Reflux, urologic and male genital diseases, medicine.disease, Vesicoureteral reflux, female genital diseases and pregnancy complications, Pediatric urology, Urinary calcium, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, 030225 pediatrics, Pediatrics, Perinatology and Child Health, medicine, Surgery, Hypercalciuria, Risk factor, business
الوصف: Introduction A large number of genes and environmental factors, like dietary habits, play a role in the development of hypercalciuria in children. In this study, we aimed to determine the effects of the presence and grade of vesicoureteral reflux (VUR) on hypercalciuria status in children. Materials and Methods Data for 165 patients who admitted to the Pediatric Urology Department were retrospectively analyzed. The patients were composed of following four different groups: (1) urinary stone patients, (2) VUR patients under follow-up, (3) corrected VUR patients, and (4) control. The demographic features, clinical data, and laboratory tests for the groups were compared. Results The mean age of the patients was 100.6 ± 54.69 months and the female/male ratio was 79:86. The mean urinary calcium/creatinine (UCa/Cr) excretion and the frequency of high UCa/Cr ratios in the corrected VUR group were similar to those in the control group (p = 0.375 and 0.965, respectively). In contrast, the mean UCa/Cr excretion and frequency of high UCa/Cr ratios in the urinary stone and follow-up VUR groups were significantly higher than those in the corrected VUR group (p Conclusion Both the mean UCa/Cr ratio and the rate of hypercalciuria in the corrected reflux group were significantly lower than the corresponding values in the follow-up VUR and urinary stone groups. Further, the follow-up VUR patients had similar urinary calcium excretion levels as the stone patients. VUR treatment is associated with a decrease in urinary calcium excretion to the normal population level. A positive correlation between reflux degree and calcium excretion was observed.
تدمد: 1439-359X
0939-7248
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::79146b122415bb34df9e8420d51477aeTest
https://doi.org/10.1055/s-0040-1721389Test
رقم الانضمام: edsair.doi...........79146b122415bb34df9e8420d51477ae
قاعدة البيانات: OpenAIRE