التفاصيل البيبلوغرافية
| العنوان: |
Ictal technetium-99m ethyl cysteinate dimer single-photon emission tomographic findings and propagation of epileptic seizure activity in patients with extratemporal epilepsies. |
| المؤلفون: |
Noachtar, Soheyl, Arnold, Stephan, Yousry, Tarek A., Bartenstein, Peter, Werhahn, Konrad J., Tatsch, Klaus |
| المصدر: |
European Journal of Nuclear Medicine. 1998, Vol. 25 Issue 2, p166-172. 7p. |
| مصطلحات موضوعية: |
*POSITRON emission tomography, *TEMPORAL lobe epilepsy, *ELECTROENCEPHALOGRAPHY, *CEREBRAL circulation, *DIAGNOSIS |
| مستخلص: |
Abstract. Although ictal single-photon emission tomography (SPET) with technetium-99m ethyl cysteinate dimer (ECD) has a well-established role in the diagnostic evaluation of patients with temporal lobe epilepsy who are being considered for epilepsy surgery, its use in cases of extratemporal epilepsy is still limited. We investigated the influence of the propagation of extratemporal epileptic seizure activity on the regional increase in cerebral blood flow, which is usually associated with epileptic seizure activity. Forty-two consecutive patients with extratemporal epilepsies were prospectively evaluated. All patients underwent ictal SPET studies with simultaneous electroencephalography (EEG) and video recordings of habitual seizures and imaging studies including cranial magnetic resonance imaging and positron emission tomography with 2-[[sup 18]F]-fluoro-2 deoxy-D-glucose. Propagation of epilptic seizure activity (PESA) was defined as the absence of hyperperfusion on ictal ECD SPET in the lobe of seizure onset, but its presence in another ipsilateral or contralateral lobe. Observers analysing the SPET images were not informed of the other results. PESA was observed in 8 of the 42 patients (19%) and was ipsilateral to the seizure onset in five (63%) of these eight patients. The time between clinical seizure onset and injection... [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
