المؤلفون: Veldhoven, J.P.D. van, Campostrini, G., Gessel, C.J.E. van, Ward-van Oostwaard, D., Liu, R.F., Mummery, C.L., Bellin, M., IJzerman, A.P.

المصدر: European Journal of Medicinal Chemistry

مصطلحات موضوعية: K(v)11.1 (hERG) channel, Allosteric modulation, LUF7346, Cardiotoxicity, Dofetilide, Human induced pluripotent stem cells (hiPSCs), hiPSC-derived cardiomyocytes

وصف الملف: application/pdf

العلاقة: https://www.sciencedirect.com/science/article/pii/S0223523420310059?via%3DihubTest; lumc-id: 121016484; https://hdl.handle.net/1887/3221400Test

الإتاحة: https://doi.org/10.1016/j.ejmech.2020.113033Test
https://hdl.handle.net/1887/3221400Test
https://www.sciencedirect.com/science/article/pii/S0223523420310059?via%3DihubTest

المؤلفون: Lieve Naesens, María Jesús Pérez de Vega, Rosario González-Muñiz, Adrián Plata, Francisco Sala, Sara González-Rodríguez, Antonio Ferrer-Montiel, José Mulet, Beatriz Balsera, Asia Fernández-Carvajal, Salvador Sala, Roberto de la Torre-Martínez, Manuel Criado

المساهمون: Ministerio de Economía, Industria y Competitividad (España), Generalitat Valenciana, European Commission

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
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مصطلحات موضوعية: Male, 0301 basic medicine, alpha7 Nicotinic Acetylcholine Receptor, Xenopus, Freund's Adjuvant, Allosteric regulation, Pain, Peptide, Diketopiperazines, Pharmacology, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Valine, Drug Discovery, DDP-IV, Animals, Edema, Humans, Structure–activity relationship, Prodrugs, Amino Acids, Rats, Wistar, Allosteric modulation, Ion channel, Pain Measurement, Inflammation, chemistry.chemical_classification, Analgesics, Dose-Response Relationship, Drug, Molecular Structure, Phenylpropionates, Diphenylpropanones, Organic Chemistry, Biological activity, General Medicine, Prodrug, Rats, Amino acid, 030104 developmental biology, chemistry, Biochemistry, a7 nicotinic receptors, Peptides, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688a9f55c560582aabb7cc3d4a8781feTest
https://doi.org/10.1016/j.ejmech.2017.10.083Test