Electronic Excitation Gives Informative Fragmentation of Polypeptide Cations and Anions
| العنوان: | Electronic Excitation Gives Informative Fragmentation of Polypeptide Cations and Anions |
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| المؤلفون: | Jesper V. Olsen, Roman A. Zubarev, Michael L. Nielsen, Kim F. Haselmann, Bogdan A. Budnik, Frank Kjeldsen |
| المصدر: | Haselmann, K F, Budnik, B A, Kjeldsen, F, Nielsen, M L, Olsen, J V & Zubarev, R A 2002, ' Electronic excitation gives informative fragmentation of polypeptide cations and anions ', European Journal of Mass Spectrometry, vol. 8, pp. 117-121 . https://doi.org/10.1255/ejms.479Test |
| بيانات النشر: | SAGE Publications, 2002. |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | Electron-capture dissociation, Collision-induced dissociation, Chemistry, 010401 analytical chemistry, Analytical chemistry, General Medicine, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Atomic and Molecular Physics, and Optics, Dissociation (chemistry), 0104 chemical sciences, symbols.namesake, Crystallography, Fourier transform, Fragmentation (mass spectrometry), symbols, Molecule, Spectroscopy, Excitation |
| الوصف: | A Fourier transform mass spectrometer is a versatile instrument with a range of available fragmentation techniques. Comparison of polypeptide fragmentation patterns revealed that the techniques involving electronic excitation, such as hot-electron-capture dissociation (HECD) and electron-detachment dissociation (EDD), are even more informative than vibrational excitation (VE) techniques such as collisional activation. For dications of the peptide KIMHASELMANN, 11 eV HECD cleaved all inter-residue links in at least two places, with up to five fragments characterizing each link. For dianions of the same molecule, VE produced only one backbone cleavage whereas EDD gave ten, including five internal cleavage fragments. This is consistent with the general postulate that homogeneous electronic excitation yields more types of cleavage than near-equilibrium processes such as VE. |
| تدمد: | 1751-6838 1469-0667 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8504a41178d1a871469845e43304f10Test https://doi.org/10.1255/ejms.479Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....f8504a41178d1a871469845e43304f10 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17516838 14690667 |
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