Impact of age on the cumulative risk of transformation in patients with chronic myelomonocytic leukaemia

التفاصيل البيبلوغرافية
العنوان: Impact of age on the cumulative risk of transformation in patients with chronic myelomonocytic leukaemia
المؤلفون: Ernst Ulsperger, Elmir Graf, Reinhard Stauder, Eva Jäger, Klaus Geissler, Heinz Tüchler, Josef Thaler, Ulrich Germing, Peter Valent, Ansgar Weltermann, Christoph Geissler, Sonja Heibl, Renate Marschon, Agnes Barna, Armin Zebisch, Michael Pfeilstöcker, Leopold Öhler, Rajko Kusec, Otto Zach, Bruno Schneeweiss, Michael Gurbisz, Temeida Graf, Peter Bettelheim, Heinz Sill, Sigrid Machherndl-Spandl, Gerald Webersinke, Gregor Hoermann, Thomas Nösslinger
المصدر: European Journal of Haematology
بيانات النشر: John Wiley and Sons Inc., 2021.
سنة النشر: 2021
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, blast cell count, Leukemia, Myelomonocytic, Chronic / epidemiology, Leukemia, Myelomonocytic, Chronic / mortality, Comorbidity, Lower risk, Competing risks, Myelomonocytic leukaemia, cytogenetics, 03 medical and health sciences, 0302 clinical medicine, Older patients, Internal medicine, hemic and lymphatic diseases, Biomarkers, Tumor, Odds Ratio, Medicine, score, Humans, In patient, Aged, Aged, 80 and over, Leukemia, Myelomonocytic, Chronic / etiology, business.industry, Age Factors, Leukemia, Myelomonocytic, Chronic, Hematology, General Medicine, Original Articles, Middle Aged, mutations, Prognosis, Peripheral blood, Leukemia, Myelomonocytic, Chronic / pathology, Cumulative risk, age, 030220 oncology & carcinogenesis, Health Impact Assessment, Life expectancy, Disease Progression, Original Article, Female, Disease Susceptibility, business, chronic myelomonocytic leukaemia, 030215 immunology
الوصف: In older patients with chronic myelomonocytic leukaemia (CMML) and limited life expectancy due to age and or comorbidities, it is particularly important to consider the risk of transformation for individualised treatment decisions. There is limited information on potential differences between younger and older CMML patients regarding the cumulative risk of transformation as well as haematological, molecular and biologic characteristics. We analysed data from the Austrian Biodatabase for CMML (ABCMML) to compare these parameters in 518 CMML patients. Categorisation of patients into 3 age‐related groups
وصف الملف: application/pdf
اللغة: English
تدمد: 1600-0609
0902-4441
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0499bf4bc452a507e0fef47b6ab23a47Test
http://europepmc.org/articles/PMC8480146Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....0499bf4bc452a507e0fef47b6ab23a47
قاعدة البيانات: OpenAIRE