Risk factors for decompensation and death following umbilical hernia repair in patients with end-stage liver disease

التفاصيل البيبلوغرافية
العنوان: Risk factors for decompensation and death following umbilical hernia repair in patients with end-stage liver disease
المؤلفون: Abdullah K, Malik, Chris, Varghese, Sanjay, Pandanaboyana, Gourab, Sen, Stuart, Robinson, Stuart, McPherson, Jessica, Dyson, Derek M, Manas, Steven, Masson, John S, Hammond
المصدر: European journal of gastroenterologyhepatology. 34(10)
سنة النشر: 2022
مصطلحات موضوعية: End Stage Liver Disease, Hepatology, Elective Surgical Procedures, Risk Factors, Gastroenterology, Humans, Hernia, Umbilical, Retrospective Studies
الوصف: Symptomatic umbilical hernias are a common cause of morbidity and mortality in patients with cirrhosis and end-stage liver disease (ESLD). This study set out to characterise the factors predicting outcome following repair of symptomatic umbilical hernias in ESLD at a single institution.A retrospective review was performed of all patients with ESLD who underwent repair of a symptomatic umbilical hernia between 1998 and 2020. Overall survival was predicted using the Kaplan-Meier method. Logistic regression was used to determine predictors of decompensation and 30-day, 90-day and 1-year mortality.One-hundred-and-eight patients with ESLD underwent umbilical hernia repair (emergency n = 78, 72.2%). Transjugular shunting was performed in 29 patients (26.9%). Decompensation occurred in 44 patients (40.7%) and was predicted by emergency surgery (OR, 13.29; P = 0.001). Length of stay was shorter in elective patients compared to emergency patients (3-days vs. 7-days; P = 0.003). Thirty-day, 90-day and 1-year survival was 95.2, 93.2 and 85.4%, respectively. Model for ESLD score15 predicted 90-day mortality (OR, 18.48; P = 0.030) and hyponatraemia predicted 1-year mortality (OR, 5.31; P = 0.047). Transjugular shunting predicted survival at 1 year (OR, 0.15; P = 0.038).Repair of symptomatic umbilical hernias in patients with ESLD can be undertaken with acceptable outcomes in a specialist centre, however, this remains a high-risk intervention. Patients undergoing emergency repair are more likely to decompensate postoperatively, develop wound-related problems and have a longer length of stay. Transjugular shunting may confer a benefit to survival, but further prospective trials are warranted.
تدمد: 1473-5687
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4684685d8b8b278c633c97ed8b335d3cTest
https://pubmed.ncbi.nlm.nih.gov/36062496Test
رقم الانضمام: edsair.doi.dedup.....4684685d8b8b278c633c97ed8b335d3c
قاعدة البيانات: OpenAIRE