A controlled study of the ocular effects of tamoxifen in conventional dosage in the treatment of breast carcinoma

التفاصيل البيبلوغرافية
العنوان: A controlled study of the ocular effects of tamoxifen in conventional dosage in the treatment of breast carcinoma
المؤلفون: Longstaff, Simon, Sigurdsson, Harold, O'Keeffe, Michael, Ogston, Simon, Preece, Paul
المصدر: European Journal of Cancer and Clinical Oncology; December 1989, Vol. 25 Issue: 12 p1805-1808, 4p
مستخلص: The use of tamoxifen is expanding in its application in the treatment of breast carcinoma, and proposed prophylactic use. Tamoxifen in high dosage and in some reports at conventional dosage is associated with ocular toxicity. This study in a single blind fashion examined 79patients receiving tamoxifen for varying treatment durations at conventional dosage and 115patients not receiving tamoxifen. No ocular toxicity was found. Further follow up studies are required to ensure no toxicity develops in patients receiving high cumulative dosage on conventional therapy.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:02775379
DOI:10.1016/0277-5379(89)90351-9