Calf venous compliance measured by venous occlusion plethysmography: methodological aspects
| العنوان: | Calf venous compliance measured by venous occlusion plethysmography: methodological aspects |
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| المؤلفون: | Mikael Ekman, Helene Zachrisson, Johan Skoog, Lea Ewerman, Toste Länne, Marcus Lindenberger |
| المصدر: | European Journal of Applied Physiology. 115:245-256 |
| بيانات النشر: | Springer Science and Business Media LLC, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, Validation study, Physiology, Blood Pressure, Venous occlusion plethysmography, Veins, Young Adult, Physiology (medical), Pressure, Humans, Medicine, Orthopedics and Sports Medicine, Fluid filtration, Leg, Venous pressure, business.industry, Models, Cardiovascular, Public Health, Environmental and Occupational Health, Data interpretation, General Medicine, Plethysmography, Compliance (physiology), Blood pressure, Regional Blood Flow, Data Interpretation, Statistical, Anesthesia, Cuff, Female, business |
| الوصف: | Calf venous compliance (C calf) is commonly evaluated with venous occlusion plethysmography (VOP) during a standard cuff deflation protocol. However, the technique relies on two not previously validated assumptions concerning thigh cuff pressure (P cuff) transmission and the impact of net fluid filtration (F filt) on C calf. The aim was to validate VOP in the lower limb and to develop a model to correct for F filt during VOP.Strain-gauge technique was used to study calf volume changes in 15 women and 10 age-matched men. A thigh cuff was inflated to 60 mmHg for 4 and 8 min with a subsequent decrease of 1 mmHg s(-1). Intravenous pressure (P iv) was measured simultaneously. C calf was determined with the commonly used equation [Compliance = β 1 + 2β 2 × P cuff] describing the pressure-compliance relationship. A model was developed to identify and correct for F filt.Transmission of P cuff to P iv was 100 %. The decrease in P cuff correlated well with P iv reduction (r = 0.99, P0.001). Overall, our model showed that C calf was underestimated when F filt was not accounted for (all P0.01). F filt was higher in women (P0.01) and showed a more pronounced effect on C calf compared to men (P0.05). The impact of F filt was similar during 4- and 8-min VOP.P cuff is an adequate substitute for P iv in the lower limb. F filt is associated with an underestimation of C calf and differences in the effect of F filt during VOP can be accounted for with the correction model. Thus, our model seems to be a valuable tool in future studies of venous wall function. |
| تدمد: | 1439-6327 1439-6319 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478ed00cc7e7369ac490e26d58fa2e62Test https://doi.org/10.1007/s00421-014-3009-4Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....478ed00cc7e7369ac490e26d58fa2e62 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14396327 14396319 |
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