The association of long-term outcome and biological sex in patients with acute heart failure from different geographic regions
| العنوان: | The association of long-term outcome and biological sex in patients with acute heart failure from different geographic regions |
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| المؤلفون: | Aušra Kavoliūnienė, Carolyn S.P. Lam, Christian Mueller, Òscar Miró, Vera Regitz-Zagrosek, Aldo P. Maggioni, Alexandre Mebazaa, Alain Cohen-Solal, Adriaan A. Voors, Yuya Matsue, Katsuya Kajimoto, Jiri Parenica, Gregg C. Fonarow, W. Frank Peacock, Eiichi Akiyama, Johan Lassus, Dong-Ju Choi, Etienne Gayat, Ali Ahmed, Jelena Čelutkienė, Justina Motiejūnaitė, Justin A. Ezekowitz, Naoki Sato |
| المساهمون: | Cardiovascular Centre (CVC), Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Lithuanian University of Health Sciences [Kaunas, Lithuania], Yokohama City University (YCU), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Research Center [Associazione Nazionale Medici Cardiologi Ospedalieri] (ANMCO Research Center), Associazione Nazionale Medici Cardiologi Ospedalieri [Firenze] (ANMCO), University of Basel (Unibas), Seoul National University Bundang Hospital (SNUBH), Lithuanian University of health Sciences [Kaunas], Vilnius University [Vilnius], University Hospital Brno, Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Sekikawa Hospital [Tokyo, Japan] (SH), Nippon Medical School [Tokyo, Japan], University of Barcelona, Baylor College of Medicine (BCM), Baylor University, Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Boston University School of Medicine (BUSM), Boston University [Boston] (BU), King‘s College London, University of Alberta, Linköping University (LIU), University of California (UC), Service d'Anesthésie-Réanimation [AP-HP Hôpitaux Saint-Louis Lariboisière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], leboeuf, Christophe |
| المصدر: | European Heart Journal European Heart Journal, 41(13), 1357-1364. Oxford University Press European Heart Journal, 2020, 41 (13), pp.1357-1364. ⟨10.1093/eurheartj/ehaa071⟩ |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, CONTEMPORARY MANAGEMENT, Asia, Prognosis, 030204 cardiovascular system & hematology, Lower risk, Ventricular Function, Left, EJECTION FRACTION, 03 medical and health sciences, AGE, 0302 clinical medicine, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Internal medicine, ESC Report, Medicine, Humans, In patient, 030212 general & internal medicine, Prospective Studies, Registries, PREDICTORS, Heart Failure, Ejection fraction, business.industry, GENDER-RELATED DIFFERENCES, MORTALITY, Hazard ratio, Acute heart failure, Gender, Stroke Volume, medicine.disease, Biological sex, Comorbidity, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, 3. Good health, Clinical trial, Europe, Editorial, Heart failure, Acute Disease, Female, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Aims Recent data from national registries suggest that acute heart failure (AHF) outcomes might vary in men and women, however, it is not known whether this observation is universal. The aim of this study was to evaluate the association of biological sex and 1-year all-cause mortality in patients with AHF in various regions of the world. Methods and results We analysed several AHF cohorts including GREAT registry (22 523 patients, mostly from Europe and Asia) and OPTIMIZE-HF (26 376 patients from the USA). Clinical characteristics and medication use at discharge were collected. Hazard ratios (HRs) for 1-year mortality according to biological sex were calculated using a Cox proportional hazards regression model with adjustment for baseline characteristics (e.g. age, comorbidities, clinical and laboratory parameters at admission, left ventricular ejection fraction). In the GREAT registry, women had a lower risk of death in the year following AHF [HR 0.86 (0.79–0.94), P Conclusion Globally women with AHF have a lower 1-year mortality and less evidenced-based treatment than men. Differences among countries need further investigation. Our findings merit consideration when designing future global clinical trials in AHF. |
| وصف الملف: | application/pdf |
| تدمد: | 1522-9645 0195-668X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7aec94455a8592009ae2597d6e9468Test https://pubmed.ncbi.nlm.nih.gov/32357237Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8c7aec94455a8592009ae2597d6e9468 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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